Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7516.098 | 0.9659 | 0.9457 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7516.098 | 0.9465 | 0.9148 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7516.098 | 0.9572 | 0.9319 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7516.098 | 0.9359 | 0.8978 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7516.098 | 0.9666 | 0.9469 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7516.098 | 0.7916 | 0.6620 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7516.098 | 0.7213 | 0.5439 | 1.2625 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7517.098 | 1.0284 | 1.0440 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7517.098 | 0.9384 | 0.9035 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7517.098 | 0.9667 | 0.9480 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7517.098 | 1.0252 | 1.0391 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7517.098 | 1.0087 | 1.0135 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7517.098 | 0.9407 | 0.9071 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7517.098 | 0.8762 | 0.8045 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7517.098 | 0.6412 | 0.4153 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7517.098 | 0.5074 | 0.1796 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7518.098 | 0.9741 | 0.9677 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7518.098 | 0.9073 | 0.8828 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7518.098 | 0.9613 | 0.9515 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7518.098 | 0.9853 | 0.9817 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7518.098 | 0.9839 | 0.9799 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7518.098 | 0.9183 | 0.8970 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7518.098 | 0.7958 | 0.7355 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7518.098 | 0.7319 | 0.6478 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7518.098 | 0.5155 | 0.3255 | 1.6108 |