Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 0.48 | uM | 12269.143 | 0.9429 | 0.6532 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 2.4 | uM | 12269.143 | 0.9862 | 0.9121 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 12 | uM | 12269.143 | 0.8826 | 0.3346 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 60 | uM | 12269.143 | 1.0659 | 1.4593 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 300 | uM | 12269.143 | 0.5746 | -0.6677 | 0.3088 | ||
| SUM185PE | TNBC | Luminal | Ibandronate | FDPS | 1500 | uM | 12269.143 | 0.4362 | -0.8638 | 0.3088 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10579.143 | 1.1230 | 1.3261 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10579.143 | 0.9924 | 0.9802 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.096 | uM | 10579.143 | 1.0156 | 1.0408 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.48 | uM | 10579.143 | 1.0012 | 1.0031 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 2.4 | uM | 10579.143 | 1.0020 | 1.0052 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 12 | uM | 10579.143 | 0.9165 | 0.7852 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 60 | uM | 10579.143 | 0.9237 | 0.8036 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 300 | uM | 10579.143 | 0.8320 | 0.5740 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 1500 | uM | 10579.143 | 0.7371 | 0.3443 | 0.7678 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.00384 | uM | 12098.143 | 1.0453 | 1.0923 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.0192 | uM | 12098.143 | 1.0978 | 1.1994 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.096 | uM | 12098.143 | 1.0220 | 1.0447 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 0.48 | uM | 12098.143 | 1.1016 | 1.2071 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 2.4 | uM | 12098.143 | 1.0094 | 1.0191 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 12 | uM | 12098.143 | 0.9850 | 0.9695 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 60 | uM | 12098.143 | 0.7982 | 0.5898 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 300 | uM | 12098.143 | 0.8350 | 0.6646 | 0.9820 | ||
| SUM225CWN | HER2amp | Basal A | Ibandronate | FDPS | 1500 | uM | 12098.143 | 0.6485 | 0.2867 | 0.9820 | ||
| SUM229PE | TNBC | - | Ibandronate | FDPS | 0.00384 | uM | 11058.143 | 0.9770 | 0.9802 | 2.3374 |