Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10819.15 | 0.8656 | 0.8687 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10819.15 | 0.6507 | 0.6339 | 2.1256 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 11937.16 | 0.9562 | 0.9633 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 11937.16 | 1.0208 | 1.0171 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 11937.16 | 0.9946 | 0.9955 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 11937.16 | 1.0785 | 1.0636 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 11937.16 | 0.9344 | 0.9446 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 11937.16 | 0.9071 | 0.9209 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 11937.16 | 0.9526 | 0.9602 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 11937.16 | 0.7056 | 0.7310 | 2.4144 | ||
| SUM149PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 11937.16 | 0.5228 | 0.5288 | 2.4144 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10520.138 | 1.2339 | 1.1308 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10520.138 | 0.9252 | 0.9537 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10520.138 | 1.0988 | 1.0576 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10520.138 | 1.2474 | 1.1378 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10520.138 | 1.2078 | 1.1171 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10520.138 | 1.0687 | 1.0404 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10520.138 | 0.5656 | 0.6844 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10520.138 | 0.2851 | 0.3703 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10520.138 | 0.3716 | 0.4841 | 3.3183 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 11057.15 | 1.0127 | 1.0063 | 4.0042 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 11057.15 | 1.0399 | 1.0196 | 4.0042 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 11057.15 | 1.0397 | 1.0195 | 4.0042 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 11057.15 | 0.9757 | 0.9877 | 4.0042 | ||
| SUM159PT | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 11057.15 | 0.9736 | 0.9867 | 4.0042 |