Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9648.011 | 1.0203 | 1.0589 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9648.011 | 0.9003 | 0.7185 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9648.011 | 0.6478 | 0.0678 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9648.011 | 0.4184 | -0.4322 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9648.011 | 0.4116 | -0.4454 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9648.011 | 0.3916 | -0.4841 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9648.011 | 0.3670 | -0.5301 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9648.011 | 0.3836 | -0.4991 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9648.011 | 0.3724 | -0.5201 | 0.6920 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7897.011 | 1.0247 | 1.0753 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7897.011 | 0.9822 | 0.9462 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7897.011 | 1.0385 | 1.1181 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7897.011 | 0.9629 | 0.8884 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7897.011 | 0.9118 | 0.7386 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7897.011 | 0.9557 | 0.8670 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7897.011 | 0.8074 | 0.4456 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7897.011 | 0.7095 | 0.1881 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7897.011 | 0.7509 | 0.2950 | 0.6591 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 9664.12 | 0.9511 | 0.8218 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 9664.12 | 1.0048 | 1.0180 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 9664.12 | 0.9814 | 0.9311 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 9664.12 | 0.8675 | 0.5347 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 9664.12 | 0.8131 | 0.3602 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 9664.12 | 0.8385 | 0.4405 | 0.5368 | |
| MDA-MB-415 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 9664.12 | 0.7163 | 0.0743 | 0.5368 |