Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9648.012 | 0.1073 | -0.9634 | 0.5579 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10095.012 | 1.0187 | 1.0417 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10095.012 | 0.9942 | 0.9870 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10095.012 | 0.9725 | 0.9387 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10095.012 | 0.1714 | -0.7204 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10095.012 | 0.1615 | -0.7383 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10095.012 | 0.1777 | -0.7088 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10095.012 | 0.1746 | -0.7145 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10095.012 | 0.1596 | -0.7417 | 0.8966 | |
| MDA-MB-361 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10095.012 | 0.1526 | -0.7542 | 0.8966 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7897.012 | 0.9943 | 0.9855 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7897.012 | 0.9909 | 0.9767 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7897.012 | 0.9622 | 0.9038 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7897.012 | 0.4124 | -0.3568 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7897.012 | 0.3087 | -0.5561 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7897.012 | 0.2910 | -0.5886 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7897.012 | 0.2869 | -0.5960 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7897.012 | 0.2496 | -0.6620 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7897.012 | 0.2552 | -0.6521 | 0.7808 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9664.049 | 1.0805 | 1.2272 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9664.049 | 0.9891 | 0.9698 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9664.049 | 1.0538 | 1.1512 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9664.049 | 0.9523 | 0.8685 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9664.049 | 0.3873 | -0.4651 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9664.049 | 0.4133 | -0.4146 | 0.7193 |