Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10019.049 | 1.0363 | 1.1604 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10019.049 | 0.9350 | 0.7297 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10019.049 | 0.3788 | -0.7546 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10019.049 | 0.3487 | -0.7949 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10019.049 | 0.3126 | -0.8380 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10019.049 | 0.2829 | -0.8694 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10019.049 | 0.2176 | -0.9260 | 0.4626 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9294.012 | 1.0025 | 1.0055 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9294.012 | 1.0075 | 1.0167 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9294.012 | 0.9875 | 0.9723 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9294.012 | 0.7878 | 0.5360 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9294.012 | 0.5107 | -0.0495 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9294.012 | 0.4478 | -0.1780 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9294.012 | 0.4400 | -0.1940 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9294.012 | 0.4391 | -0.1957 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9294.012 | 0.4176 | -0.2393 | 0.9035 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10031.012 | 1.0587 | 1.1670 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10031.012 | 1.1204 | 1.3466 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10031.012 | 1.0069 | 1.0194 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10031.012 | 0.7111 | 0.2381 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10031.012 | 0.5730 | -0.0861 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10031.012 | 0.6028 | -0.0186 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10031.012 | 0.5544 | -0.1275 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10031.012 | 0.5778 | -0.0753 | 0.7110 | |
| HCC1428 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10031.012 | 0.5665 | -0.1006 | 0.7110 |