Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7923.016 | 0.6734 | 0.0656 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7923.016 | 0.5872 | -0.1434 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7923.016 | 0.5982 | -0.1177 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7923.016 | 0.9317 | 0.7868 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7923.016 | 0.4968 | -0.3435 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7923.016 | 0.2264 | -0.8122 | 0.6280 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9878.019 | 0.9647 | 0.9520 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9878.019 | 0.9561 | 0.9402 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9878.019 | 0.9809 | 0.9741 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9878.019 | 0.9833 | 0.9773 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9878.019 | 1.0010 | 1.0014 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9878.019 | 0.9435 | 0.9229 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9878.019 | 1.0112 | 1.0152 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9878.019 | 0.8514 | 0.7938 | 1.4790 | |
| SUM52PE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9878.019 | 0.2841 | -0.1460 | 1.4790 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9033.016 | 1.0086 | 1.0126 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9033.016 | 0.9619 | 0.9442 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9033.016 | 0.9064 | 0.8619 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9033.016 | 0.9594 | 0.9406 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9033.016 | 0.9421 | 0.9151 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9033.016 | 0.9414 | 0.9140 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9033.016 | 0.8998 | 0.8521 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9033.016 | 0.8635 | 0.7974 | 1.3741 | |
| T47D | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9033.016 | 0.4386 | 0.0979 | 1.3741 | |
| UACC-893 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9045.016 | 0.9011 | 0.7820 | 0.9026 |