Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7529.016 | 0.9723 | 0.9063 | 0.5847 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7529.016 | 0.9651 | 0.8820 | 0.5847 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7529.016 | 0.9399 | 0.7989 | 0.5847 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7529.016 | 0.8130 | 0.4036 | 0.5847 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7529.016 | 0.6416 | -0.0638 | 0.5847 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9797.019 | 0.9646 | 0.8583 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9797.019 | 0.9818 | 0.9267 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9797.019 | 0.9463 | 0.7873 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9797.019 | 0.9867 | 0.9464 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9797.019 | 1.0129 | 1.0530 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9797.019 | 0.8431 | 0.4131 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9797.019 | 0.7273 | 0.0460 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9797.019 | 0.5726 | -0.3572 | 0.4912 | |
| SUM1315MO2 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9797.019 | 0.2502 | -0.8809 | 0.4912 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7917.016 | 1.0375 | 1.0251 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7917.016 | 0.9584 | 0.9715 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7917.016 | 0.9491 | 0.9650 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7917.016 | 0.9695 | 0.9791 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7917.016 | 0.9272 | 0.9495 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7917.016 | 0.7850 | 0.8426 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7917.016 | 0.6219 | 0.7028 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7917.016 | 0.6155 | 0.6969 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7917.016 | 0.2642 | 0.2744 | 2.9532 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9830.019 | 1.0328 | 1.0341 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9830.019 | 1.0718 | 1.0742 | 1.9053 |