Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7821.016 | 1.0301 | 1.2005 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7821.016 | 0.8620 | 0.2389 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7821.016 | 0.7163 | -0.3182 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7821.016 | 0.3695 | -0.9194 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9278.132 | 0.9587 | 0.7906 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9278.132 | 0.9643 | 0.8181 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9278.132 | 0.9768 | 0.8804 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9278.132 | 0.9950 | 0.9737 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9278.132 | 0.9978 | 0.9885 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9278.132 | 0.9715 | 0.8540 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9278.132 | 0.8826 | 0.4415 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9278.132 | 0.9425 | 0.7122 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9278.132 | 0.8338 | 0.2421 | 0.3815 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 10019.049 | 1.1706 | 1.8110 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 10019.049 | 0.9778 | 0.9052 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 10019.049 | 1.0678 | 1.3045 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 10019.049 | 1.0220 | 1.0962 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 10019.049 | 1.0209 | 1.0914 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 10019.049 | 1.0883 | 1.4012 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 10019.049 | 0.9641 | 0.8479 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 10019.049 | 0.6669 | -0.1669 | 0.4626 | |
| HCC1419 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 10019.049 | 0.2309 | -0.9159 | 0.4626 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9294.019 | 0.9504 | 0.8852 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9294.019 | 0.9212 | 0.8181 | 0.8608 | |
| HCC1428 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9294.019 | 0.9601 | 0.9077 | 0.8608 |