Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.107	uM	12379.167	0.9824	0.9331	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.533	uM	12379.167	0.9736	0.8999	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	2.67	uM	12379.167	1.0285	1.1107	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	13.3	uM	12379.167	0.9466	0.8000	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	66.7	uM	12379.167	0.9196	0.7027	0.5212
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10938.154	0.8860	0.7807	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10938.154	0.8109	0.6357	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10938.154	0.9051	0.8176	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10938.154	0.8347	0.6817	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10938.154	0.8632	0.7368	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10938.154	0.8205	0.6543	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10938.154	0.8376	0.6873	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10938.154	0.9080	0.8231	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10938.154	0.8684	0.7468	1.0425
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000171	uM	12333.167	0.9025	0.7203	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000853	uM	12333.167	0.9426	0.8337	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00427	uM	12333.167	1.0307	1.0909	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0213	uM	12333.167	0.8879	0.6796	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.107	uM	12333.167	0.9405	0.8278	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.533	uM	12333.167	0.9187	0.7659	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	2.67	uM	12333.167	0.8798	0.6571	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	13.3	uM	12333.167	0.8385	0.5442	0.6809
MDA-MB-415	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	66.7	uM	12333.167	0.8763	0.6474	0.6809
MDA-MB-453	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000171	uM	12414.167	0.9575	0.9297	1.2130
MDA-MB-453	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000853	uM	12414.167	0.9962	0.9938	1.2130

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)