Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
184A1
NM
Basal
FR180204
ERK1/2
MAPK
0.00128
uM
12509.166
1.0195 1.0303 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
0.0064
uM
12509.166
1.0063 1.0098 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
0.032
uM
12509.166
1.1006 1.1550 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
0.16
uM
12509.166
1.0300 1.0466 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
0.8
uM
12509.166
0.9195 0.8735 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
4
uM
12509.166
1.0643 1.0993 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
20
uM
12509.166
0.8978 0.8390 1.2847
184A1
NM
Basal
FR180204
ERK1/2
MAPK
100
uM
12509.166
0.5704 0.2919 1.2847
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.000256
uM
12566.166
0.9966 0.9943 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.00128
uM
12566.166
1.0327 1.0543 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.0064
uM
12566.166
0.9851 0.9751 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.032
uM
12566.166
1.0602 1.0997 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.16
uM
12566.166
1.0019 1.0032 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
0.8
uM
12566.166
0.9644 0.9406 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
4
uM
12566.166
0.9017 0.8349 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
20
uM
12566.166
0.6393 0.3780 1.2010
184B5
NM
Basal
FR180204
ERK1/2
MAPK
100
uM
12566.166
0.5439 0.2046 1.2010
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.000256
uM
12224.161
0.9563 0.8786 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.00128
uM
12224.161
0.9979 0.9942 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.0064
uM
12224.161
0.9699 0.9162 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.032
uM
12224.161
0.9596 0.8878 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.16
uM
12224.161
1.0201 1.0565 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
0.8
uM
12224.161
0.9318 0.8115 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
4
uM
12224.161
1.0075 1.0211 0.7139
600MPE
HR+
Luminal
FR180204
ERK1/2
MAPK
20
uM
12224.161
0.8849 0.6851 0.7139