Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7508.084 | 0.0044 | -0.9982 | 0.7756 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7510.084 | 1.0597 | 1.1378 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7510.084 | 1.0121 | 1.0279 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7510.084 | 0.9184 | 0.8136 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7510.084 | 0.9074 | 0.7886 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7510.084 | 0.7955 | 0.5375 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7510.084 | 0.4395 | -0.2225 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7510.084 | 0.0005 | -0.9997 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7510.084 | 0.0005 | -0.9997 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7510.084 | 0.0005 | -0.9997 | 0.8702 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7511.084 | 1.0077 | 1.0133 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7511.084 | 0.9411 | 0.8968 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7511.084 | 0.9771 | 0.9599 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7511.084 | 0.9558 | 0.9226 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7511.084 | 0.9020 | 0.8280 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7511.084 | 0.5819 | 0.2472 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7511.084 | 0.0011 | -0.9946 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7511.084 | 0.0025 | -0.9894 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7511.084 | 0.0056 | -0.9783 | 1.1467 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7512.084 | 0.9954 | 0.9876 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7512.084 | 1.0436 | 1.1169 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7512.084 | 1.0265 | 1.0709 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7512.084 | 1.0301 | 1.0806 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7512.084 | 0.8327 | 0.5673 | 0.7511 | |
| MDA-MB-415 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7512.084 | 0.0386 | -0.9737 | 0.7511 |