Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7458.084 | 0.9625 | 0.8692 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7458.084 | 0.7721 | 0.2655 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7458.084 | 0.0089 | -0.9995 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7458.084 | 0.0079 | -0.9996 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7458.084 | 0.0123 | -0.9992 | 0.5653 | |
| HCC202 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7458.084 | 0.0035 | -0.9999 | 0.5653 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7462.085 | 1.0173 | 1.0899 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7462.085 | 0.9448 | 0.7287 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7462.085 | 1.0068 | 1.0353 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7462.085 | 0.8822 | 0.4500 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7462.085 | 0.8365 | 0.2648 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7462.085 | 0.6260 | -0.3989 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7462.085 | 0.0079 | -1.0000 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7462.085 | 0.0077 | -1.0000 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7462.085 | 0.0074 | -1.0000 | 0.3896 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7463.084 | 0.9720 | 0.9262 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7463.084 | 0.9342 | 0.8278 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7463.084 | 0.9721 | 0.9266 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7463.084 | 0.9085 | 0.7616 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7463.084 | 0.8441 | 0.5983 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7463.084 | 0.6930 | 0.2313 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7463.084 | 0.0020 | -0.9995 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7463.084 | 0.0064 | -0.9975 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7463.084 | 0.0012 | -0.9997 | 0.7560 | |
| HCC2185 | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7464.084 | 0.9957 | 0.9895 | 0.8152 |