Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PLX-4720 | 0.1 | uM | 2 | 2500.00 | 1446.42 | 8311.33 | 7615.00 | 1.0923 | 1.0730 |
| MCF 10A | PLX-4720 | 0.31623 | uM | 2 | 2500.00 | 1446.42 | 8272.33 | 7615.00 | 1.0867 | 1.0703 |
| MCF 10A | PLX-4720 | 1 | uM | 2 | 2500.00 | 1446.42 | 8599.67 | 7615.00 | 1.1294 | 1.1042 |
| MCF 10A | PLX-4720 | 3.1623 | uM | 2 | 2500.00 | 1446.42 | 8768.33 | 7615.00 | 1.1510 | 1.1204 |
| MCF 10A | PLX-4720 | 10 | uM | 2 | 2500.00 | 1446.42 | 9034.00 | 7615.00 | 1.1865 | 1.1480 |
| MCF 10A | PLX-4720 | 19.9526 | uM | 2 | 2500.00 | 1446.42 | 6745.67 | 7615.00 | 0.8861 | 0.9015 |
| MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 2500.00 | 1446.42 | 7619.00 | 7615.00 | 0.9996 | 0.9984 |
| MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 2500.00 | 1446.42 | 8063.67 | 7615.00 | 1.0597 | 1.0483 |
| MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 2500.00 | 1446.42 | 7882.00 | 7615.00 | 1.0368 | 1.0285 |
| MCF 10A | NVP-TAE684 | 0.031623 | uM | 2 | 2500.00 | 1446.42 | 7114.67 | 7615.00 | 0.9345 | 0.9443 |
| MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 2500.00 | 1446.42 | 6530.33 | 7615.00 | 0.8582 | 0.8760 |
| MCF 10A | NVP-TAE684 | 0.31623 | uM | 2 | 2500.00 | 1446.42 | 5008.67 | 7615.00 | 0.6574 | 0.6783 |
| MCF 10A | NVP-TAE684 | 1 | uM | 2 | 2500.00 | 1446.42 | 2893.33 | 7615.00 | 0.3800 | 0.3346 |
| MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 2500.00 | 1446.42 | 1231.33 | 7615.00 | 0.1618 | -0.0665 |
| MCF 10A | NVP-TAE684 | 10 | uM | 2 | 2500.00 | 1446.42 | 722.00 | 7615.00 | 0.0944 | -0.2600 |
| MCF 10A | Palbociclib | 0.0033113 | uM | 2 | 2500.00 | 1446.42 | 6744.33 | 7161.00 | 0.9437 | 0.9493 |
| MCF 10A | Palbociclib | 0.01 | uM | 2 | 2500.00 | 1446.42 | 6140.00 | 7161.00 | 0.8592 | 0.8709 |
| MCF 10A | Palbociclib | 0.031623 | uM | 2 | 2500.00 | 1446.42 | 4948.67 | 7161.00 | 0.6918 | 0.7029 |
| MCF 10A | Palbociclib | 0.1 | uM | 2 | 2500.00 | 1446.42 | 4692.33 | 7161.00 | 0.6499 | 0.6411 |
| MCF 10A | Palbociclib | 0.31623 | uM | 2 | 2500.00 | 1446.42 | 3282.00 | 7161.00 | 0.4594 | 0.4269 |
| MCF 10A | Palbociclib | 1 | uM | 2 | 2500.00 | 1446.42 | 2788.00 | 7161.00 | 0.3882 | 0.3179 |
| MCF 10A | Palbociclib | 3.1623 | uM | 2 | 2500.00 | 1446.42 | 2293.67 | 7161.00 | 0.3199 | 0.2196 |
| MCF 10A | Palbociclib | 10 | uM | 2 | 2500.00 | 1446.42 | 1735.33 | 7161.00 | 0.2430 | 0.0814 |
| MCF 10A | Palbociclib | 19.9526 | uM | 2 | 2500.00 | 1446.42 | 1558.33 | 7161.00 | 0.2164 | 0.0264 |
| MCF 10A | Omipalisib | 0.0016596 | uM | 2 | 5000.00 | 3410.67 | 5164.67 | 5991.17 | 0.8592 | 0.6517 |