Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | PLX-4720 | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 7358.33 | 7602.33 | 0.9677 | 0.9823 |
MCF 10A | PLX-4720 | 0.01 | uM | 2 | 1250.00 | 585.71 | 7313.67 | 7602.33 | 0.9626 | 0.9771 |
MCF 10A | PLX-4720 | 0.031623 | uM | 2 | 1250.00 | 585.71 | 7051.00 | 7602.33 | 0.9311 | 0.9606 |
MCF 10A | PLX-4720 | 0.1 | uM | 2 | 1250.00 | 585.71 | 7687.67 | 7602.33 | 1.0138 | 1.0044 |
MCF 10A | PLX-4720 | 0.31623 | uM | 2 | 1250.00 | 585.71 | 8163.33 | 7602.33 | 1.0758 | 1.0395 |
MCF 10A | PLX-4720 | 1 | uM | 2 | 1250.00 | 585.71 | 8198.67 | 7602.33 | 1.0802 | 1.0416 |
MCF 10A | PLX-4720 | 3.1623 | uM | 2 | 1250.00 | 585.71 | 8593.00 | 7602.33 | 1.1319 | 1.0678 |
MCF 10A | PLX-4720 | 10 | uM | 2 | 1250.00 | 585.71 | 7114.67 | 7602.33 | 0.9373 | 0.9651 |
MCF 10A | PLX-4720 | 19.9526 | uM | 2 | 1250.00 | 585.71 | 3460.00 | 7602.33 | 0.4564 | 0.6157 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 1250.00 | 585.71 | 6995.33 | 7602.33 | 0.9186 | 0.9537 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 8051.00 | 7602.33 | 1.0613 | 1.0322 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 1250.00 | 585.71 | 7673.00 | 7602.33 | 1.0082 | 1.0035 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 2 | 1250.00 | 585.71 | 6898.33 | 7602.33 | 0.9084 | 0.9444 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 1250.00 | 585.71 | 5945.00 | 7602.33 | 0.7796 | 0.8680 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 2 | 1250.00 | 585.71 | 4503.67 | 7602.33 | 0.5911 | 0.7338 |
MCF 10A | NVP-TAE684 | 1 | uM | 2 | 1250.00 | 585.71 | 1745.33 | 7602.33 | 0.2319 | 0.3172 |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 1250.00 | 585.71 | 812.33 | 7602.33 | 0.1075 | 0.0888 |
MCF 10A | NVP-TAE684 | 10 | uM | 2 | 1250.00 | 585.71 | 327.67 | 7602.33 | 0.0432 | -0.1455 |
MCF 10A | Palbociclib | 0.0033113 | uM | 2 | 1250.00 | 585.71 | 7172.33 | 6891.50 | 1.0420 | 1.0216 |
MCF 10A | Palbociclib | 0.01 | uM | 2 | 1250.00 | 585.71 | 6397.67 | 6891.50 | 0.9283 | 0.9586 |
MCF 10A | Palbociclib | 0.031623 | uM | 2 | 1250.00 | 585.71 | 6050.00 | 6891.50 | 0.8757 | 0.9219 |
MCF 10A | Palbociclib | 0.1 | uM | 2 | 1250.00 | 585.71 | 5001.00 | 6891.50 | 0.7295 | 0.8130 |
MCF 10A | Palbociclib | 0.31623 | uM | 2 | 1250.00 | 585.71 | 2899.00 | 6891.50 | 0.4214 | 0.5578 |
MCF 10A | Palbociclib | 1 | uM | 2 | 1250.00 | 585.71 | 1697.00 | 6891.50 | 0.2480 | 0.3269 |
MCF 10A | Palbociclib | 3.1623 | uM | 2 | 1250.00 | 585.71 | 1373.33 | 6891.50 | 0.1994 | 0.2671 |