Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Nilotinib | 0.1 | uM | 2 | 312.50 | 134.46 | 2352.00 | 1710.33 | 1.3813 | 1.1836 |
MCF 10A | Nilotinib | 0.31623 | uM | 2 | 312.50 | 134.46 | 2077.33 | 1710.33 | 1.2348 | 1.1169 |
MCF 10A | Nilotinib | 1 | uM | 2 | 312.50 | 134.46 | 1862.33 | 1710.33 | 1.0730 | 1.0276 |
MCF 10A | Nilotinib | 3.1623 | uM | 2 | 312.50 | 134.46 | 1945.33 | 1710.33 | 1.1501 | 1.0781 |
MCF 10A | Nilotinib | 10 | uM | 2 | 312.50 | 134.46 | 351.33 | 1710.33 | 0.1961 | 0.2601 |
MCF 10A | Nilotinib | 19.9526 | uM | 2 | 312.50 | 134.46 | 200.67 | 1710.33 | 0.1153 | 0.1020 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 2 | 312.50 | 134.46 | 1946.67 | 1710.33 | 1.1414 | 1.0736 |
MCF 10A | PLX-4720 | 0.01 | uM | 2 | 312.50 | 134.46 | 1862.00 | 1710.33 | 1.0731 | 1.0330 |
MCF 10A | PLX-4720 | 0.031623 | uM | 2 | 312.50 | 134.46 | 1612.67 | 1710.33 | 0.9508 | 0.9723 |
MCF 10A | PLX-4720 | 0.1 | uM | 2 | 312.50 | 134.46 | 2025.33 | 1710.33 | 1.1847 | 1.0952 |
MCF 10A | PLX-4720 | 0.31623 | uM | 2 | 312.50 | 134.46 | 1882.00 | 1710.33 | 1.1089 | 1.0581 |
MCF 10A | PLX-4720 | 1 | uM | 2 | 312.50 | 134.46 | 1981.33 | 1710.33 | 1.1775 | 1.0830 |
MCF 10A | PLX-4720 | 3.1623 | uM | 2 | 312.50 | 134.46 | 2069.00 | 1710.33 | 1.2281 | 1.1163 |
MCF 10A | PLX-4720 | 10 | uM | 2 | 312.50 | 134.46 | 1605.67 | 1710.33 | 0.9473 | 0.9709 |
MCF 10A | PLX-4720 | 19.9526 | uM | 2 | 312.50 | 134.46 | 811.33 | 1710.33 | 0.4823 | 0.6280 |
MCF 10A | NVP-TAE684 | 0.0016596 | uM | 2 | 312.50 | 134.46 | 1844.67 | 1710.33 | 1.0646 | 1.0263 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 2 | 312.50 | 134.46 | 2158.33 | 1710.33 | 1.2701 | 1.1363 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 2 | 312.50 | 134.46 | 2024.33 | 1710.33 | 1.1907 | 1.0989 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 2 | 312.50 | 134.46 | 1870.33 | 1710.33 | 1.0981 | 1.0523 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 2 | 312.50 | 134.46 | 1244.00 | 1710.33 | 0.7310 | 0.8360 |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 2 | 312.50 | 134.46 | 747.67 | 1710.33 | 0.4302 | 0.5786 |
MCF 10A | NVP-TAE684 | 1 | uM | 2 | 312.50 | 134.46 | 411.33 | 1710.33 | 0.2457 | 0.3595 |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 2 | 312.50 | 134.46 | 101.00 | 1710.33 | 0.0576 | -0.0881 |
MCF 10A | NVP-TAE684 | 10 | uM | 2 | 312.50 | 134.46 | 67.33 | 1710.33 | 0.0419 | -0.1850 |
MCF 10A | Palbociclib | 0.0033113 | uM | 2 | 312.50 | 134.46 | 899.67 | 1303.25 | 0.7162 | 0.7997 |