Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | 17-AAG | 3.1623 | uM | 10 | 625.00 | 241.23 | 323.00 | 1138.92 | 0.2839 | 0.1388 |
| MDA-MB-231 | 17-AAG | 10 | uM | 10 | 625.00 | 241.23 | 260.67 | 1138.92 | 0.2295 | 0.0354 |
| MDA-MB-231 | Erlotinib | 0.0033113 | uM | 10 | 625.00 | 241.23 | 1175.00 | 1138.92 | 1.0257 | 1.0108 |
| MDA-MB-231 | Erlotinib | 0.01 | uM | 10 | 625.00 | 241.23 | 1214.67 | 1138.92 | 1.0675 | 1.0581 |
| MDA-MB-231 | Erlotinib | 0.031623 | uM | 10 | 625.00 | 241.23 | 1165.33 | 1138.92 | 1.0227 | 1.0196 |
| MDA-MB-231 | Erlotinib | 0.1 | uM | 10 | 625.00 | 241.23 | 1239.33 | 1138.92 | 1.0871 | 1.0744 |
| MDA-MB-231 | Erlotinib | 0.31623 | uM | 10 | 625.00 | 241.23 | 1325.67 | 1138.92 | 1.1618 | 1.1371 |
| MDA-MB-231 | Erlotinib | 1 | uM | 10 | 625.00 | 241.23 | 1202.00 | 1138.92 | 1.0562 | 1.0484 |
| MDA-MB-231 | Erlotinib | 3.1623 | uM | 10 | 625.00 | 241.23 | 1266.33 | 1138.92 | 1.1049 | 1.0813 |
| MDA-MB-231 | Erlotinib | 10 | uM | 10 | 625.00 | 241.23 | 1007.00 | 1138.92 | 0.8826 | 0.8884 |
| MDA-MB-231 | Erlotinib | 19.9526 | uM | 10 | 625.00 | 241.23 | 826.33 | 1138.92 | 0.7286 | 0.7355 |
| MDA-MB-231 | Lapatinib | 0.0016596 | uM | 10 | 625.00 | 241.23 | 1353.67 | 1138.92 | 1.1865 | 1.1548 |
| MDA-MB-231 | Lapatinib | 0.0033113 | uM | 10 | 625.00 | 241.23 | 1253.67 | 1138.92 | 1.1010 | 1.0876 |
| MDA-MB-231 | Lapatinib | 0.01 | uM | 10 | 625.00 | 241.23 | 1231.67 | 1138.92 | 1.0765 | 1.0612 |
| MDA-MB-231 | Lapatinib | 0.031623 | uM | 10 | 625.00 | 241.23 | 1294.33 | 1138.92 | 1.1346 | 1.1116 |
| MDA-MB-231 | Lapatinib | 0.1 | uM | 10 | 625.00 | 241.23 | 1257.33 | 1138.92 | 1.0995 | 1.0817 |
| MDA-MB-231 | Lapatinib | 0.31623 | uM | 10 | 625.00 | 241.23 | 1517.67 | 1138.92 | 1.3322 | 1.2731 |
| MDA-MB-231 | Lapatinib | 1 | uM | 10 | 625.00 | 241.23 | 1338.33 | 1138.92 | 1.1683 | 1.1337 |
| MDA-MB-231 | Lapatinib | 3.1623 | uM | 10 | 625.00 | 241.23 | 1193.33 | 1138.92 | 1.0444 | 1.0352 |
| MDA-MB-231 | Lapatinib | 10 | uM | 10 | 625.00 | 241.23 | 681.67 | 1138.92 | 0.5980 | 0.5888 |
| MDA-MB-231 | Omipalisib | 0.0016596 | uM | 10 | 625.00 | 241.23 | 1194.33 | 1226.00 | 0.9996 | 0.9858 |
| MDA-MB-231 | Omipalisib | 0.0033113 | uM | 10 | 625.00 | 241.23 | 1091.00 | 1226.00 | 0.8533 | 0.7398 |
| MDA-MB-231 | Omipalisib | 0.01 | uM | 10 | 625.00 | 241.23 | 954.33 | 1226.00 | 0.7400 | 0.6376 |
| MDA-MB-231 | Omipalisib | 0.031623 | uM | 10 | 625.00 | 241.23 | 773.00 | 1226.00 | 0.6009 | 0.4189 |
| MDA-MB-231 | Omipalisib | 0.1 | uM | 10 | 625.00 | 241.23 | 525.00 | 1226.00 | 0.4344 | 0.2550 |