Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 312.50 | 96.23 | 1089.83 | 905.08 | 1.2036 | 1.1080 |
| MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 312.50 | 96.23 | 952.83 | 905.08 | 1.0498 | 1.0251 |
| MCF 10A | Lapatinib | 0.01 | uM | 9 | 312.50 | 96.23 | 1160.83 | 905.08 | 1.2821 | 1.1546 |
| MCF 10A | Lapatinib | 0.031623 | uM | 9 | 312.50 | 96.23 | 806.33 | 905.08 | 0.9017 | 0.9206 |
| MCF 10A | Lapatinib | 0.1 | uM | 9 | 312.50 | 96.23 | 1261.83 | 905.08 | 1.3863 | 1.2060 |
| MCF 10A | Lapatinib | 0.31623 | uM | 9 | 312.50 | 96.23 | 1182.33 | 905.08 | 1.2953 | 1.1541 |
| MCF 10A | Lapatinib | 1 | uM | 9 | 312.50 | 96.23 | 931.33 | 905.08 | 1.0405 | 1.0123 |
| MCF 10A | Lapatinib | 3.1623 | uM | 9 | 312.50 | 96.23 | 519.33 | 905.08 | 0.5777 | 0.6667 |
| MCF 10A | Lapatinib | 10 | uM | 9 | 312.50 | 96.23 | 64.50 | 905.08 | 0.0724 | -0.1210 |
| MCF 10A | Linsitinib | 0.0033113 | uM | 9 | 312.50 | 96.23 | 986.17 | 905.08 | 1.0969 | 1.0406 |
| MCF 10A | Linsitinib | 0.01 | uM | 9 | 312.50 | 96.23 | 1030.17 | 905.08 | 1.1324 | 1.0540 |
| MCF 10A | Linsitinib | 0.031623 | uM | 9 | 312.50 | 96.23 | 1032.00 | 905.08 | 1.1508 | 1.0838 |
| MCF 10A | Linsitinib | 0.1 | uM | 9 | 312.50 | 96.23 | 830.50 | 905.08 | 0.9239 | 0.9396 |
| MCF 10A | Linsitinib | 0.31623 | uM | 9 | 312.50 | 96.23 | 948.50 | 905.08 | 1.0415 | 1.0078 |
| MCF 10A | Linsitinib | 1 | uM | 9 | 312.50 | 96.23 | 413.83 | 905.08 | 0.4639 | 0.5619 |
| MCF 10A | Linsitinib | 3.1623 | uM | 9 | 312.50 | 96.23 | 239.50 | 905.08 | 0.2651 | 0.3210 |
| MCF 10A | Linsitinib | 10 | uM | 9 | 312.50 | 96.23 | 260.33 | 905.08 | 0.2974 | 0.3387 |
| MCF 10A | Linsitinib | 19.9526 | uM | 9 | 312.50 | 96.23 | 113.17 | 905.08 | 0.1251 | 0.0449 |
| MCF 10A | 17-AAG | 0.000066069 | uM | 9 | 625.00 | 186.95 | 3390.17 | 3008.54 | 1.1293 | 1.0589 |
| MCF 10A | 17-AAG | 0.0001 | uM | 9 | 625.00 | 186.95 | 3627.67 | 3008.54 | 1.2078 | 1.0960 |
| MCF 10A | 17-AAG | 0.000302 | uM | 9 | 625.00 | 186.95 | 3157.50 | 3008.54 | 1.0500 | 1.0231 |
| MCF 10A | 17-AAG | 0.001 | uM | 9 | 625.00 | 186.95 | 3052.50 | 3008.54 | 1.0143 | 1.0059 |
| MCF 10A | 17-AAG | 0.0031623 | uM | 9 | 625.00 | 186.95 | 2760.50 | 3008.54 | 0.9202 | 0.9561 |
| MCF 10A | 17-AAG | 0.01 | uM | 9 | 625.00 | 186.95 | 977.67 | 3008.54 | 0.3242 | 0.4820 |
| MCF 10A | 17-AAG | 0.031623 | uM | 9 | 625.00 | 186.95 | 159.17 | 3008.54 | 0.0530 | -0.0412 |