Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PLX-4720 | 0.31623 | uM | 1 | 625.00 | 173.50 | 570.33 | 474.25 | 1.2034 | 1.2834 |
| MCF7 | PLX-4720 | 1 | uM | 1 | 625.00 | 173.50 | 519.33 | 474.25 | 1.1244 | 1.2292 |
| MCF7 | PLX-4720 | 3.1623 | uM | 1 | 625.00 | 173.50 | 584.67 | 474.25 | 1.2627 | 1.4239 |
| MCF7 | PLX-4720 | 10 | uM | 1 | 625.00 | 173.50 | 558.00 | 474.25 | 1.1764 | 1.2489 |
| MCF7 | PLX-4720 | 19.9526 | uM | 1 | 625.00 | 173.50 | 431.33 | 474.25 | 0.9301 | 0.9279 |
| MCF7 | NVP-TAE684 | 0.0016596 | uM | 1 | 625.00 | 173.50 | 501.00 | 474.25 | 1.0946 | 1.1998 |
| MCF7 | NVP-TAE684 | 0.0033113 | uM | 1 | 625.00 | 173.50 | 410.00 | 474.25 | 0.8840 | 0.8548 |
| MCF7 | NVP-TAE684 | 0.01 | uM | 1 | 625.00 | 173.50 | 446.67 | 474.25 | 0.9501 | 0.9422 |
| MCF7 | NVP-TAE684 | 0.031623 | uM | 1 | 625.00 | 173.50 | 336.67 | 474.25 | 0.6863 | 0.4870 |
| MCF7 | NVP-TAE684 | 0.1 | uM | 1 | 625.00 | 173.50 | 352.67 | 474.25 | 0.7365 | 0.5931 |
| MCF7 | NVP-TAE684 | 0.31623 | uM | 1 | 625.00 | 173.50 | 211.00 | 474.25 | 0.4359 | 0.0939 |
| MCF7 | NVP-TAE684 | 1 | uM | 1 | 625.00 | 173.50 | 125.00 | 474.25 | 0.2662 | -0.2237 |
| MCF7 | NVP-TAE684 | 3.1623 | uM | 1 | 625.00 | 173.50 | 118.67 | 474.25 | 0.2678 | -0.2274 |
| MCF7 | NVP-TAE684 | 10 | uM | 1 | 625.00 | 173.50 | 145.67 | 474.25 | 0.3199 | -0.1153 |
| MCF7 | Palbociclib | 0.0033113 | uM | 1 | 625.00 | 173.50 | 363.00 | 296.58 | 1.2348 | 1.7423 |
| MCF7 | Palbociclib | 0.01 | uM | 1 | 625.00 | 173.50 | 309.33 | 296.58 | 1.0637 | 1.2829 |
| MCF7 | Palbociclib | 0.031623 | uM | 1 | 625.00 | 173.50 | 250.67 | 296.58 | 0.8431 | 0.5777 |
| MCF7 | Palbociclib | 0.1 | uM | 1 | 625.00 | 173.50 | 251.33 | 296.58 | 0.8377 | 0.5538 |
| MCF7 | Palbociclib | 0.31623 | uM | 1 | 625.00 | 173.50 | 207.00 | 296.58 | 0.6963 | 0.2805 |
| MCF7 | Palbociclib | 1 | uM | 1 | 625.00 | 173.50 | 169.67 | 296.58 | 0.5689 | -0.0593 |
| MCF7 | Palbociclib | 3.1623 | uM | 1 | 625.00 | 173.50 | 187.33 | 296.58 | 0.6437 | 0.1205 |
| MCF7 | Palbociclib | 10 | uM | 1 | 625.00 | 173.50 | 225.67 | 296.58 | 0.7935 | 0.6326 |
| MCF7 | Palbociclib | 19.9526 | uM | 1 | 625.00 | 173.50 | 231.67 | 296.58 | 0.8210 | 0.7351 |
| MCF7 | Omipalisib | 0.0016596 | uM | 1 | 1250.00 | 375.71 | 547.00 | 665.75 | 0.8175 | 0.5478 |
| MCF7 | Omipalisib | 0.0033113 | uM | 1 | 1250.00 | 375.71 | 476.00 | 665.75 | 0.7166 | 0.3075 |