Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Nilotinib | 0.31623 | uM | 1 | 5000.00 | 2308.21 | 2924.33 | 2662.50 | 1.0983 | 2.1895 |
| Hs 578T | Nilotinib | 1 | uM | 1 | 5000.00 | 2308.21 | 2956.00 | 2662.50 | 1.1111 | 2.5845 |
| Hs 578T | Nilotinib | 3.1623 | uM | 1 | 5000.00 | 2308.21 | 2855.00 | 2662.50 | 1.0718 | 1.7764 |
| Hs 578T | Nilotinib | 10 | uM | 1 | 5000.00 | 2308.21 | 1395.33 | 2662.50 | 0.5249 | -0.9120 |
| Hs 578T | Nilotinib | 19.9526 | uM | 1 | 5000.00 | 2308.21 | 1443.00 | 2662.50 | 0.5430 | -0.8993 |
| Hs 578T | PLX-4720 | 0.0033113 | uM | 1 | 5000.00 | 2308.21 | 2705.33 | 2662.50 | 1.0161 | 1.1704 |
| Hs 578T | PLX-4720 | 0.01 | uM | 1 | 5000.00 | 2308.21 | 2770.00 | 2662.50 | 1.0410 | 1.5201 |
| Hs 578T | PLX-4720 | 0.031623 | uM | 1 | 5000.00 | 2308.21 | 2685.00 | 2662.50 | 1.0084 | 1.0924 |
| Hs 578T | PLX-4720 | 0.1 | uM | 1 | 5000.00 | 2308.21 | 2789.00 | 2662.50 | 1.0476 | 1.5267 |
| Hs 578T | PLX-4720 | 0.31623 | uM | 1 | 5000.00 | 2308.21 | 2902.00 | 2662.50 | 1.0901 | 2.0997 |
| Hs 578T | PLX-4720 | 1 | uM | 1 | 5000.00 | 2308.21 | 3076.00 | 2662.50 | 1.1556 | 3.2298 |
| Hs 578T | PLX-4720 | 3.1623 | uM | 1 | 5000.00 | 2308.21 | 3015.67 | 2662.50 | 1.1324 | 2.6780 |
| Hs 578T | PLX-4720 | 10 | uM | 1 | 5000.00 | 2308.21 | 2869.67 | 2662.50 | 1.0781 | 2.0022 |
| Hs 578T | PLX-4720 | 19.9526 | uM | 1 | 5000.00 | 2308.21 | 2534.33 | 2662.50 | 0.9530 | 0.6846 |
| Hs 578T | NVP-TAE684 | 0.0016596 | uM | 1 | 5000.00 | 2308.21 | 2631.67 | 2662.50 | 0.9883 | 0.8884 |
| Hs 578T | NVP-TAE684 | 0.0033113 | uM | 1 | 5000.00 | 2308.21 | 2689.67 | 2662.50 | 1.0097 | 1.0711 |
| Hs 578T | NVP-TAE684 | 0.01 | uM | 1 | 5000.00 | 2308.21 | 2585.67 | 2662.50 | 0.9710 | 0.7227 |
| Hs 578T | NVP-TAE684 | 0.031623 | uM | 1 | 5000.00 | 2308.21 | 2556.00 | 2662.50 | 0.9598 | 0.6282 |
| Hs 578T | NVP-TAE684 | 0.1 | uM | 1 | 5000.00 | 2308.21 | 2551.67 | 2662.50 | 0.9582 | 0.6115 |
| Hs 578T | NVP-TAE684 | 0.31623 | uM | 1 | 5000.00 | 2308.21 | 2404.00 | 2662.50 | 0.9030 | 0.2094 |
| Hs 578T | NVP-TAE684 | 1 | uM | 1 | 5000.00 | 2308.21 | 2260.00 | 2662.50 | 0.8491 | -0.1016 |
| Hs 578T | NVP-TAE684 | 3.1623 | uM | 1 | 5000.00 | 2308.21 | 1739.33 | 2662.50 | 0.6541 | -0.7473 |
| Hs 578T | NVP-TAE684 | 10 | uM | 1 | 5000.00 | 2308.21 | 1180.33 | 2662.50 | 0.4454 | -0.9558 |
| Hs 578T | Palbociclib | 0.0033113 | uM | 1 | 5000.00 | 2308.21 | 1815.67 | 1972.67 | 0.9015 | 0.5451 |
| Hs 578T | Palbociclib | 0.01 | uM | 1 | 5000.00 | 2308.21 | 1705.67 | 1972.67 | 0.8637 | 0.2614 |