Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Taxol | 1 | uM | 10 | 156.25 | 46.73 | 74.33 | 254.33 | 0.3434 | 0.1794 |
| MCF7 | Linsitinib | 0.0033113 | uM | 10 | 156.25 | 46.73 | 124.00 | 104.00 | 1.2107 | 1.4088 |
| MCF7 | Linsitinib | 0.01 | uM | 10 | 156.25 | 46.73 | 160.67 | 104.00 | 1.4883 | 1.6999 |
| MCF7 | Linsitinib | 0.031623 | uM | 10 | 156.25 | 46.73 | 140.00 | 104.00 | 1.3646 | 1.6824 |
| MCF7 | Linsitinib | 0.1 | uM | 10 | 156.25 | 46.73 | 132.67 | 104.00 | 1.2783 | 1.4937 |
| MCF7 | Linsitinib | 0.31623 | uM | 10 | 156.25 | 46.73 | 136.00 | 104.00 | 1.3303 | 1.6309 |
| MCF7 | Linsitinib | 1 | uM | 10 | 156.25 | 46.73 | 107.00 | 104.00 | 1.0477 | 1.1197 |
| MCF7 | Linsitinib | 3.1623 | uM | 10 | 156.25 | 46.73 | 80.00 | 104.00 | 0.7936 | 0.6586 |
| MCF7 | Linsitinib | 10 | uM | 10 | 156.25 | 46.73 | 76.00 | 104.00 | 0.7420 | 0.5483 |
| MCF7 | Linsitinib | 19.9526 | uM | 10 | 156.25 | 46.73 | 58.00 | 104.00 | 0.5783 | 0.2434 |
| MCF7 | Palbociclib | 0.0033113 | uM | 10 | 156.25 | 46.73 | 274.33 | 254.33 | 1.1561 | 1.2385 |
| MCF7 | Palbociclib | 0.01 | uM | 10 | 156.25 | 46.73 | 291.00 | 254.33 | 1.2387 | 1.3505 |
| MCF7 | Palbociclib | 0.031623 | uM | 10 | 156.25 | 46.73 | 248.00 | 254.33 | 1.1327 | 1.3126 |
| MCF7 | Palbociclib | 0.1 | uM | 10 | 156.25 | 46.73 | 308.67 | 254.33 | 1.2680 | 1.3339 |
| MCF7 | Palbociclib | 0.31623 | uM | 10 | 156.25 | 46.73 | 223.67 | 254.33 | 0.9927 | 1.1291 |
| MCF7 | Palbociclib | 1 | uM | 10 | 156.25 | 46.73 | 133.33 | 254.33 | 0.5344 | 0.4352 |
| MCF7 | Palbociclib | 3.1623 | uM | 10 | 156.25 | 46.73 | 92.33 | 254.33 | 0.3813 | 0.2344 |
| MCF7 | Palbociclib | 10 | uM | 10 | 156.25 | 46.73 | 88.00 | 254.33 | 0.4454 | 0.3734 |
| MCF7 | Palbociclib | 19.9526 | uM | 10 | 156.25 | 46.73 | 121.00 | 254.33 | 0.5559 | 0.5011 |
| MCF7 | 17-AAG | 0.0016596 | uM | 10 | 312.50 | 95.00 | 291.00 | 231.25 | 1.2507 | 1.3586 |
| MCF7 | 17-AAG | 0.0033113 | uM | 10 | 312.50 | 95.00 | 263.33 | 231.25 | 1.1462 | 1.2332 |
| MCF7 | 17-AAG | 0.01 | uM | 10 | 312.50 | 95.00 | 158.33 | 231.25 | 0.6921 | 0.5034 |
| MCF7 | 17-AAG | 0.031623 | uM | 10 | 312.50 | 95.00 | 145.33 | 231.25 | 0.6242 | 0.3756 |
| MCF7 | 17-AAG | 0.1 | uM | 10 | 312.50 | 95.00 | 79.33 | 231.25 | 0.3440 | -0.1316 |
| MCF7 | 17-AAG | 0.31623 | uM | 10 | 312.50 | 95.00 | 96.33 | 231.25 | 0.4164 | 0.0082 |