Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 0.31623 | uM | 1 | 5000.00 | 1498.27 | 4511.33 | 5071.08 | 0.8899 | 0.8714 |
| MCF7 | Nilotinib | 1 | uM | 1 | 5000.00 | 1498.27 | 4763.67 | 5071.08 | 0.9391 | 0.9292 |
| MCF7 | Nilotinib | 3.1623 | uM | 1 | 5000.00 | 1498.27 | 3981.00 | 5071.08 | 0.7855 | 0.7425 |
| MCF7 | Nilotinib | 10 | uM | 1 | 5000.00 | 1498.27 | 1629.33 | 5071.08 | 0.3213 | 0.0471 |
| MCF7 | Nilotinib | 19.9526 | uM | 1 | 5000.00 | 1498.27 | 1686.00 | 5071.08 | 0.3326 | 0.0694 |
| MCF7 | PLX-4720 | 0.0033113 | uM | 1 | 5000.00 | 1498.27 | 5191.67 | 5071.08 | 1.0238 | 1.0267 |
| MCF7 | PLX-4720 | 0.01 | uM | 1 | 5000.00 | 1498.27 | 5336.67 | 5071.08 | 1.0521 | 1.0581 |
| MCF7 | PLX-4720 | 0.031623 | uM | 1 | 5000.00 | 1498.27 | 5326.67 | 5071.08 | 1.0507 | 1.0568 |
| MCF7 | PLX-4720 | 0.1 | uM | 1 | 5000.00 | 1498.27 | 4955.00 | 5071.08 | 0.9771 | 0.9737 |
| MCF7 | PLX-4720 | 0.31623 | uM | 1 | 5000.00 | 1498.27 | 4907.00 | 5071.08 | 0.9676 | 0.9626 |
| MCF7 | PLX-4720 | 1 | uM | 1 | 5000.00 | 1498.27 | 5027.00 | 5071.08 | 0.9909 | 0.9888 |
| MCF7 | PLX-4720 | 3.1623 | uM | 1 | 5000.00 | 1498.27 | 5254.00 | 5071.08 | 1.0362 | 1.0403 |
| MCF7 | PLX-4720 | 10 | uM | 1 | 5000.00 | 1498.27 | 5090.33 | 5071.08 | 1.0040 | 1.0046 |
| MCF7 | PLX-4720 | 19.9526 | uM | 1 | 5000.00 | 1498.27 | 4368.00 | 5071.08 | 0.8616 | 0.8377 |
| MCF7 | NVP-TAE684 | 0.0016596 | uM | 1 | 5000.00 | 1498.27 | 5139.00 | 5071.08 | 1.0130 | 1.0133 |
| MCF7 | NVP-TAE684 | 0.0033113 | uM | 1 | 5000.00 | 1498.27 | 4991.00 | 5071.08 | 0.9845 | 0.9821 |
| MCF7 | NVP-TAE684 | 0.01 | uM | 1 | 5000.00 | 1498.27 | 5114.67 | 5071.08 | 1.0092 | 1.0103 |
| MCF7 | NVP-TAE684 | 0.031623 | uM | 1 | 5000.00 | 1498.27 | 4583.00 | 5071.08 | 0.9046 | 0.8881 |
| MCF7 | NVP-TAE684 | 0.1 | uM | 1 | 5000.00 | 1498.27 | 3437.67 | 5071.08 | 0.6779 | 0.6032 |
| MCF7 | NVP-TAE684 | 0.31623 | uM | 1 | 5000.00 | 1498.27 | 2512.00 | 5071.08 | 0.4952 | 0.3410 |
| MCF7 | NVP-TAE684 | 1 | uM | 1 | 5000.00 | 1498.27 | 1725.67 | 5071.08 | 0.3402 | 0.0824 |
| MCF7 | NVP-TAE684 | 3.1623 | uM | 1 | 5000.00 | 1498.27 | 1278.33 | 5071.08 | 0.2522 | -0.0869 |
| MCF7 | NVP-TAE684 | 10 | uM | 1 | 5000.00 | 1498.27 | 1238.33 | 5071.08 | 0.2443 | -0.1027 |
| MCF7 | Palbociclib | 0.0033113 | uM | 1 | 5000.00 | 1498.27 | 4169.00 | 4705.25 | 0.8889 | 0.8627 |
| MCF7 | Palbociclib | 0.01 | uM | 1 | 5000.00 | 1498.27 | 4395.67 | 4705.25 | 0.9328 | 0.9112 |