Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
BT-20 | Omipalisib | 3.1623 | uM | 5 | 2500.00 | 1400.29 | 777.67 | 4476.92 | 0.1738 | -0.2967 |
SK-BR-3 | Omipalisib | 0.1 | uM | 3 | 2500.00 | 2418.67 | 1805.00 | 4308.42 | 0.4190 | -0.2962 |
MCF 10A | Omipalisib | 10 | uM | 2 | 625.00 | 277.50 | 83.00 | 3384.25 | 0.0247 | -0.2953 |
SK-BR-3 | Taxol | 0.1 | uM | 3 | 625.00 | 556.96 | 405.33 | 1063.67 | 0.3810 | -0.2946 |
SK-BR-3 | Etoposide | 10 | uM | 3 | 2500.00 | 2418.67 | 1767.67 | 4525.50 | 0.3905 | -0.2936 |
SK-BR-3 | Omipalisib | 0.31623 | uM | 4 | 625.00 | 368.38 | 282.33 | 629.50 | 0.4490 | -0.2921 |
SK-BR-3 | Omipalisib | 1 | uM | 4 | 1250.00 | 814.29 | 575.33 | 1645.75 | 0.3503 | -0.2893 |
Hs 578T | Omipalisib | 3.1623 | uM | 1 | 2500.00 | 1203.29 | 935.67 | 2259.00 | 0.3827 | -0.2889 |
SK-BR-3 | 17-AAG | 0.31623 | uM | 7 | 312.50 | 169.63 | 137.67 | 265.67 | 0.5197 | -0.2872 |
BT-20 | Omipalisib | 1 | uM | 4 | 156.25 | 44.67 | 35.00 | 75.92 | 0.4793 | -0.2863 |
SK-BR-3 | Taxol | 1 | uM | 3 | 2500.00 | 2418.67 | 1828.33 | 4308.42 | 0.4245 | -0.2853 |
Hs 578T | NVP-TAE684 | 3.1623 | uM | 1 | 156.25 | 76.08 | 48.00 | 202.42 | 0.2401 | -0.2836 |
SK-BR-3 | Omipalisib | 0.1 | uM | 4 | 625.00 | 368.38 | 285.67 | 629.50 | 0.4536 | -0.2834 |
BT-20 | Taxol | 0.31623 | uM | 4 | 5000.00 | 2571.29 | 1547.33 | 7426.83 | 0.2084 | -0.2827 |
MDA-MB-231 | NVP-TAE684 | 10 | uM | 2 | 1250.00 | 570.38 | 320.33 | 1917.17 | 0.1670 | -0.2819 |
MCF 10A | Omipalisib | 0.031623 | uM | 2 | 2500.00 | 1446.42 | 706.67 | 7161.00 | 0.0975 | -0.2805 |
SK-BR-3 | Taxol | 1 | uM | 4 | 312.50 | 180.13 | 153.00 | 254.83 | 0.6002 | -0.2799 |
BT-20 | Taxol | 1 | uM | 3 | 625.00 | 278.42 | 189.00 | 689.17 | 0.2707 | -0.2791 |
SK-BR-3 | NVP-TAE684 | 10 | uM | 4 | 5000.00 | 3240.08 | 2525.67 | 5492.00 | 0.4599 | -0.2791 |
MCF7 | NVP-TAE684 | 3.1623 | uM | 1 | 1250.00 | 375.71 | 240.00 | 1006.83 | 0.2463 | -0.2788 |
BT-20 | Omipalisib | 1 | uM | 4 | 625.00 | 288.04 | 181.33 | 772.58 | 0.2375 | -0.2783 |
Hs 578T | Omipalisib | 10 | uM | 1 | 2500.00 | 1203.29 | 958.00 | 2259.00 | 0.3939 | -0.2781 |
MCF7 | Taxol | 0.031623 | uM | 1 | 1250.00 | 375.71 | 297.00 | 665.75 | 0.4423 | -0.2773 |
SK-BR-3 | Omipalisib | 0.01 | uM | 3 | 156.25 | 80.34 | 74.33 | 93.25 | 0.8024 | -0.2772 |
SK-BR-3 | Etoposide | 1 | uM | 4 | 5000.00 | 3240.08 | 2531.67 | 5492.00 | 0.4608 | -0.2768 |