PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | CDK6 | DLKPQNILVTSSGQIK | Lys2 | -6.4 | 1 | uM |
| PF-3758309 | THP-1 | CDK7 | DLKPNNLLLDENGVLK | Lys2 | 96.5 | 1 | uM |
| PF-3758309 | THP-1 | CDK9 | DMKAANVLITR | Lys2 | -5.6 | 1 | uM |
| PF-3758309 | THP-1 | CHK2 | VAIKIISK | Lys1 | 91.1 | 1 | uM |
| PF-3758309 | THP-1 | CHK2 | DLKPENVLLSSQEEDCLIK | Lys2 | 81.8 | 1 | uM |
| PF-3758309 | THP-1 | CRK7 | DIKCSNILLNNSGQIK | Lys2 | 8.2 | 1 | uM |
| PF-3758309 | THP-1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 12.7 | 1 | uM |
| PF-3758309 | THP-1 | DNAPK | EHPFLVKGGEDLR | ATP | 9.2 | 1 | uM |
| PF-3758309 | THP-1 | eEF2K | YIKYNSNSGFVR | ATP | -2.2 | 1 | uM |
| PF-3758309 | THP-1 | FAK | CIGEGQFGDVHQGIYMSPENPALAVAIKTCK | Lys1 | 23.2 | 1 | uM |
| PF-3758309 | THP-1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | 63.9 | 1 | uM |
| PF-3758309 | THP-1 | FER | TSVAVKTCKEDLPQELK | Lys1 | 73.7 | 1 | uM |
| PF-3758309 | THP-1 | FES | LRADNTLVAVKSCR | Lys1 | 2.3 | 1 | uM |
| PF-3758309 | THP-1 | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 6.8 | 1 | uM |
| PF-3758309 | THP-1 | FRAP1 | IQSIAPSLQVITSKQRPR | ATP | 9.4 | 1 | uM |
| PF-3758309 | THP-1 | FYV1 | GGKSGAAFYATEDDRFILK | ATP | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | GCK | DTVTSELAAVKIVK | Lys1 | 1.6 | 1 | uM |
| PF-3758309 | THP-1 | GSK3A | DIKPQNLLVDPDTAVLK | Lys2 | 52.6 | 1 | uM |
| PF-3758309 | THP-1 | GSK3B | DIKPQNLLLDPDTAVLK | Lys2 | 74.7 | 1 | uM |
| PF-3758309 | THP-1 | HPK1 | DKVSGDLVALKMVK | Lys1 | 15.1 | 1 | uM |
| PF-3758309 | THP-1 | IKKB | WHNQETGEQIAIKQCR | Lys1 | 2.5 | 1 | uM |
| PF-3758309 | THP-1 | IKKE | SGELVAVKVFNTTSYLRPR | Lys1 | 87.7 | 1 | uM |
| PF-3758309 | THP-1 | IKKE,TBK1 | DIKPGNIMR | Lys2 | 87.6 | 1 | uM |
| PF-3758309 | THP-1 | ILK | WQGNDIVVKVLK | Lys1 | -3.6 | 1 | uM |
| PF-3758309 | THP-1 | INSR | VAVKTVNESASLR | Lys1 | 9.1 | 1 | uM |