LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 CGP60474
10
uM
LJP6
 0.0894 0.0185 -0.4845 0.0358
MCF7 PD173074
0.04
uM
LJP6
 1.0921 0.0379 1.0978 0.0379
MCF7 PD173074
0.12
uM
LJP6
 1.0689 0.0149 1.0759 0.0165
MCF7 PD173074
0.37
uM
LJP6
 1.0366 0.0394 1.0406 0.0451
MCF7 PD173074
1.11
uM
LJP6
 1.0922 0.0324 1.1014 0.0382
MCF7 PD173074
3.33
uM
LJP6
 1.0939 0.0621 1.1007 0.0693
MCF7 PD173074
10
uM
LJP6
 0.6484 0.0789 0.5718 0.0905
MCF7 Crizotinib
0.04
uM
LJP5
 0.7874 0.0408 0.7622 0.0404
MCF7 Crizotinib
0.12
uM
LJP5
 0.7771 0.0351 0.7475 0.0451
MCF7 Crizotinib
0.37
uM
LJP5
 0.6748 0.0465 0.6182 0.0703
MCF7 Crizotinib
1.11
uM
LJP5
 0.4843 0.0512 0.3507 0.0962
MCF7 Crizotinib
3.33
uM
LJP5
 0.2981 0.0058 0.0468 0.0274
MCF7 Crizotinib
10
uM
LJP5
 0.1897 0.0110 -0.1740 0.0374
MCF7 BMS345541
0.04
uM
LJP6
 1.0542 0.0296 1.0619 0.0335
MCF7 BMS345541
0.12
uM
LJP6
 1.0006 0.0318 1.0030 0.0349
MCF7 BMS345541
0.37
uM
LJP6
 0.8995 0.0263 0.8825 0.0332
MCF7 BMS345541
1.11
uM
LJP6
 0.6030 0.0488 0.5019 0.0836
MCF7 BMS345541
3.33
uM
LJP6
 0.2964 0.0335 0.0136 0.0718
MCF7 BMS345541
10
uM
LJP6
 0.1388 0.0397 -0.3479 0.0815
MCF7 KIN001-043
0.04
uM
LJP6
 0.9641 0.0320 0.9569 0.0366
MCF7 KIN001-043
0.12
uM
LJP6
 0.8832 0.0343 0.8644 0.0434
MCF7 KIN001-043
0.37
uM
LJP6
 0.8584 0.0480 0.8373 0.0571
MCF7 KIN001-043
1.11
uM
LJP6
 0.8695 0.0211 0.8511 0.0239
MCF7 KIN001-043
3.33
uM
LJP6
 0.8209 0.0204 0.7909 0.0287
MCF7 KIN001-043
10
uM
LJP6
 0.4145 0.0103 0.2245 0.0232