LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Enzastaurin | 1.11 | uM | LJP5 | 1.0417 | 0.0134 | 1.0601 | 0.0189 |
| SK-BR-3 | Enzastaurin | 3.33 | uM | LJP5 | 1.0537 | 0.0242 | 1.0732 | 0.0323 |
| SK-BR-3 | Enzastaurin | 10 | uM | LJP5 | 0.9722 | 0.0646 | 0.9581 | 0.1057 |
| SK-BR-3 | Palbociclib | 0.04 | uM | LJP6 | 0.8772 | 0.0565 | 0.8186 | 0.0718 |
| SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 0.7958 | 0.0284 | 0.6835 | 0.0213 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 0.7514 | 0.0343 | 0.6125 | 0.0287 |
| SK-BR-3 | Palbociclib | 1.11 | uM | LJP6 | 0.7443 | 0.0097 | 0.5946 | 0.0219 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 0.7257 | 0.0279 | 0.5677 | 0.0280 |
| SK-BR-3 | Palbociclib | 10 | uM | LJP6 | 0.6968 | 0.0139 | 0.5168 | 0.0264 |
| SK-BR-3 | PF562271 | 0.04 | uM | LJP6 | 1.0302 | 0.0173 | 1.0530 | 0.0295 |
| SK-BR-3 | PF562271 | 0.12 | uM | LJP6 | 0.9816 | 0.0392 | 0.9838 | 0.0546 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 0.8043 | 0.0534 | 0.7043 | 0.0569 |
| SK-BR-3 | PF562271 | 1.11 | uM | LJP6 | 0.5115 | 0.0258 | 0.1976 | 0.0305 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 0.3718 | 0.0139 | -0.0632 | 0.0482 |
| SK-BR-3 | PF562271 | 10 | uM | LJP6 | 0.2767 | 0.0419 | -0.2538 | 0.1456 |
| SK-BR-3 | PHA-793887 | 0.04 | uM | LJP6 | 0.4853 | 0.0243 | 0.1451 | 0.0857 |
| SK-BR-3 | PHA-793887 | 0.12 | uM | LJP6 | 0.4560 | 0.0167 | 0.0952 | 0.0490 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 0.4121 | 0.0150 | 0.0136 | 0.0455 |
| SK-BR-3 | PHA-793887 | 1.11 | uM | LJP6 | 0.3873 | 0.0296 | -0.0334 | 0.0422 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 0.3664 | 0.0260 | -0.0738 | 0.0425 |
| SK-BR-3 | PHA-793887 | 10 | uM | LJP6 | 0.2520 | 0.0257 | -0.3047 | 0.1192 |
| SK-BR-3 | QL-X-138 | 0.04 | uM | LJP6 | 0.6703 | 0.0363 | 0.4632 | 0.0899 |
| SK-BR-3 | QL-X-138 | 0.12 | uM | LJP6 | 0.6376 | 0.0271 | 0.4134 | 0.0654 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 0.5346 | 0.0120 | 0.2332 | 0.0758 |
| SK-BR-3 | QL-X-138 | 1.11 | uM | LJP6 | 0.4931 | 0.0181 | 0.1627 | 0.0523 |