LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 0.4743 | 0.0255 | 0.1270 | 0.0723 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 0.4452 | 0.0315 | 0.0732 | 0.0869 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 0.4380 | 0.0285 | 0.0598 | 0.0815 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 0.4149 | 0.0202 | 0.0172 | 0.0856 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 0.4432 | 0.0238 | 0.0703 | 0.0537 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 0.4064 | 0.0109 | 0.0009 | 0.0761 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 0.4040 | 0.0143 | -0.0064 | 0.0971 |
| SK-BR-3 | WYE-125132 | 1.11 | uM | LJP6 | 0.4024 | 0.0196 | -0.0078 | 0.0864 |
| SK-BR-3 | WYE-125132 | 3.33 | uM | LJP6 | 0.3733 | 0.0085 | -0.0626 | 0.0866 |
| SK-BR-3 | WYE-125132 | 10 | uM | LJP6 | 0.3728 | 0.0198 | -0.0635 | 0.0831 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 0.3651 | 0.0116 | -0.0450 | 0.0450 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 0.3575 | 0.0143 | -0.0601 | 0.0474 |
| SK-BR-3 | Barasertib | 0.37 | uM | LJP5 | 0.3474 | 0.0214 | -0.0794 | 0.0409 |
| SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 0.3581 | 0.0142 | -0.0587 | 0.0485 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 0.3492 | 0.0128 | -0.0758 | 0.0501 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 0.3527 | 0.0079 | -0.0692 | 0.0505 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 1.0392 | 0.0283 | 1.0507 | 0.0400 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 1.0244 | 0.0169 | 1.0340 | 0.0252 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 1.0155 | 0.0156 | 1.0261 | 0.0232 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 1.0006 | 0.0163 | 1.0055 | 0.0244 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 0.9634 | 0.0221 | 0.9513 | 0.0267 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 0.8679 | 0.0174 | 0.8054 | 0.0184 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 1.0660 | 0.0390 | 1.1004 | 0.0562 |
| SK-BR-3 | Enzastaurin | 0.12 | uM | LJP5 | 1.0483 | 0.0344 | 1.0733 | 0.0490 |
| SK-BR-3 | Enzastaurin | 0.37 | uM | LJP5 | 1.0694 | 0.0166 | 1.0983 | 0.0189 |