LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
BT-20 Trametinib
0.37
uM
LJP5
 0.7890 0.0280 0.7433 0.0274
BT-20 Trametinib
1.11
uM
LJP5
 0.7691 0.0303 0.7174 0.0306
BT-20 Trametinib
3.33
uM
LJP5
 0.7431 0.0159 0.6828 0.0108
BT-20 Trametinib
10
uM
LJP5
 0.8030 0.0359 0.7616 0.0383
BT-20 Omipalisib
0.04
uM
LJP6
 0.2705 0.0294 -0.0909 0.0475
BT-20 Omipalisib
0.12
uM
LJP6
 0.2439 0.0227 -0.1454 0.0368
BT-20 Omipalisib
0.37
uM
LJP6
 0.2089 0.0227 -0.2221 0.0469
BT-20 Omipalisib
1.11
uM
LJP6
 0.1824 0.0236 -0.2844 0.0540
BT-20 Omipalisib
3.33
uM
LJP6
 0.1682 0.0294 -0.3201 0.0786
BT-20 Omipalisib
10
uM
LJP6
 0.1495 0.0303 -0.3676 0.0848
BT-20 Buparlisib
0.04
uM
LJP5
 1.0098 0.0140 1.0119 0.0165
BT-20 Buparlisib
0.12
uM
LJP5
 0.8881 0.0521 0.8679 0.0600
BT-20 Buparlisib
0.37
uM
LJP5
 0.6112 0.0522 0.5008 0.0639
BT-20 Buparlisib
1.11
uM
LJP5
 0.3114 0.0065 0.0131 0.0219
BT-20 Buparlisib
3.33
uM
LJP5
 0.1817 0.0153 -0.2612 0.0628
BT-20 Buparlisib
10
uM
LJP5
 0.1473 0.0163 -0.3463 0.0697
BT-20 XL147
0.04
uM
LJP5
 1.0654 0.0264 1.0731 0.0268
BT-20 XL147
0.12
uM
LJP5
 1.0470 0.0351 1.0511 0.0379
BT-20 XL147
0.37
uM
LJP5
 1.0018 0.0393 0.9989 0.0445
BT-20 XL147
1.11
uM
LJP5
 0.9711 0.0294 0.9640 0.0347
BT-20 XL147
3.33
uM
LJP5
 0.8723 0.0049 0.8468 0.0055
BT-20 XL147
10
uM
LJP5
 0.3874 0.0148 0.1493 0.0499
BT-20 Y39983
0.04
uM
LJP6
 0.9940 0.0329 0.9942 0.0393
BT-20 Y39983
0.12
uM
LJP6
 1.0086 0.0460 1.0132 0.0564
BT-20 Y39983
0.37
uM
LJP6
 0.9671 0.0397 0.9620 0.0484