LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
Hs 578T Dasatinib
1.11
uM
LJP5
 0.2333 0.0817 -0.0158 0.1126
Hs 578T Dasatinib
1.11
uM
LJP6
 0.2304 0.0717 -0.0268 0.0977
Hs 578T Dasatinib
3.33
uM
LJP5
 0.2311 0.0839 -0.0229 0.1182
Hs 578T Dasatinib
3.33
uM
LJP6
 0.2006 0.0615 -0.0902 0.0943
Hs 578T Dasatinib
10
uM
LJP5
 0.2201 0.0664 -0.0384 0.0940
Hs 578T Dasatinib
10
uM
LJP6
 0.1623 0.0471 -0.1788 0.0752
Hs 578T Tozasertib
0.04
uM
LJP5
 0.2991 0.0694 0.1232 0.0661
Hs 578T Tozasertib
0.12
uM
LJP5
 0.2746 0.0642 0.0776 0.0686
Hs 578T Tozasertib
0.37
uM
LJP5
 0.2909 0.0698 0.1077 0.0733
Hs 578T Tozasertib
1.11
uM
LJP5
 0.2724 0.0641 0.0732 0.0626
Hs 578T Tozasertib
3.33
uM
LJP5
 0.2894 0.0677 0.1052 0.0698
Hs 578T Tozasertib
10
uM
LJP5
 0.2581 0.0458 0.0498 0.0442
Hs 578T Imatinib
0.04
uM
LJP6
 0.9980 0.0109 0.9972 0.0102
Hs 578T Imatinib
0.12
uM
LJP6
 0.9954 0.0067 0.9958 0.0062
Hs 578T Imatinib
0.37
uM
LJP6
 1.0048 0.0204 1.0081 0.0194
Hs 578T Imatinib
1.11
uM
LJP6
 1.0259 0.0249 1.0285 0.0238
Hs 578T Imatinib
3.33
uM
LJP6
 1.0480 0.0321 1.0512 0.0344
Hs 578T Imatinib
10
uM
LJP6
 1.0450 0.0652 1.0526 0.0624
Hs 578T NVP-TAE684
0.04
uM
LJP6
 0.8806 0.0324 0.8847 0.0234
Hs 578T NVP-TAE684
0.12
uM
LJP6
 0.6415 0.0230 0.6099 0.0567
Hs 578T NVP-TAE684
0.37
uM
LJP6
 0.6323 0.0619 0.6095 0.0419
Hs 578T NVP-TAE684
1.11
uM
LJP6
 0.4422 0.0749 0.3505 0.0610
Hs 578T NVP-TAE684
3.33
uM
LJP6
 0.2946 0.0446 0.1107 0.0240
Hs 578T NVP-TAE684
10
uM
LJP6
 0.1602 0.0572 -0.2008 0.0866
Hs 578T CGP60474
0.04
uM
LJP5
 0.8365 0.0616 0.8460 0.0479