LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 ZSTK474
1.11
uM
LJP6
 0.3099 0.0119 0.0423 0.0375
MCF7 ZSTK474
3.33
uM
LJP6
 0.2886 0.0144 0.0016 0.0410
MCF7 ZSTK474
10
uM
LJP6
 0.2801 0.0287 -0.0168 0.0633
MCF7 BX-912
0.04
uM
LJP5
 0.8342 0.0281 0.8162 0.0306
MCF7 BX-912
0.12
uM
LJP5
 0.8803 0.0255 0.8660 0.0335
MCF7 BX-912
0.37
uM
LJP5
 0.7709 0.0730 0.7312 0.0964
MCF7 BX-912
1.11
uM
LJP5
 0.5550 0.0274 0.4590 0.0583
MCF7 BX-912
3.33
uM
LJP5
 0.4401 0.0098 0.2925 0.0362
MCF7 BX-912
10
uM
LJP5
 0.2810 0.0116 0.0193 0.0173
MCF7 Selumetinib
0.04
uM
LJP6
 0.8858 0.0593 0.8670 0.0726
MCF7 Selumetinib
0.12
uM
LJP6
 0.7455 0.0289 0.6964 0.0409
MCF7 Selumetinib
0.37
uM
LJP6
 0.6461 0.0324 0.5684 0.0358
MCF7 Selumetinib
1.11
uM
LJP6
 0.6264 0.0421 0.5427 0.0415
MCF7 Selumetinib
3.33
uM
LJP6
 0.6499 0.0403 0.5754 0.0365
MCF7 Selumetinib
10
uM
LJP6
 0.6128 0.0231 0.5242 0.0135
MCF7 MK2206
0.04
uM
LJP6
 0.6855 0.0424 0.6162 0.0671
MCF7 MK2206
0.12
uM
LJP6
 0.6000 0.0235 0.5025 0.0495
MCF7 MK2206
0.37
uM
LJP6
 0.4479 0.0326 0.2781 0.0556
MCF7 MK2206
1.11
uM
LJP6
 0.4571 0.0289 0.2907 0.0680
MCF7 MK2206
3.33
uM
LJP6
 0.3861 0.0189 0.1763 0.0538
MCF7 MK2206
10
uM
LJP6
 0.2380 0.0287 -0.1039 0.0837
MCF7 AZD-6482
0.04
uM
LJP5
 1.0474 0.0408 1.0499 0.0452
MCF7 AZD-6482
0.12
uM
LJP5
 0.9609 0.0335 0.9543 0.0374
MCF7 AZD-6482
0.37
uM
LJP5
 0.9935 0.0379 0.9881 0.0381
MCF7 AZD-6482
1.11
uM
LJP5
 0.9137 0.0143 0.9064 0.0167