LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 962 | 972 | 10692 | 0.0910 | 0.0030 |
MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 962 | 819 | 10692 | 0.0766 | -0.0454 |
MCF 10A | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 962 | 460 | 10692 | 0.0431 | -0.1920 |
MCF 10A | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 962 | 552 | 10692 | 0.0517 | -0.1484 |
MCF 10A | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 962 | 10049 | 10692 | 0.9398 | 0.9645 |
MCF 10A | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 962 | 6550 | 10692 | 0.6126 | 0.7365 |
MCF 10A | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 962 | 2892 | 10692 | 0.2705 | 0.3723 |
MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 962 | 1324 | 10692 | 0.1239 | 0.0964 |
MCF 10A | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 962 | 758 | 10692 | 0.0709 | -0.0664 |
MCF 10A | Radicicol | 10 | uM | LJP6 | 72 | hr | 962 | 381 | 10692 | 0.0357 | -0.2339 |
MCF 10A | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 962 | 10553 | 10692 | 0.9870 | 0.9925 |
MCF 10A | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 962 | 10051 | 10692 | 0.9402 | 0.9646 |
MCF 10A | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 962 | 8178 | 10692 | 0.7648 | 0.8514 |
MCF 10A | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 962 | 687 | 10692 | 0.0643 | -0.0928 |
MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 962 | 599 | 10692 | 0.0561 | -0.1276 |