LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1341 | 4012 | 0.3343 | 0.0608 |
| MCF7 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1305 | 4012 | 0.3250 | 0.0435 |
| MCF7 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1241 | 4012 | 0.3095 | 0.0148 |
| MCF7 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1239 | 4012 | 0.3085 | 0.0125 |
| MCF7 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1209 | 777 | 4012 | 0.1945 | -0.2274 |
| MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1361 | 4012 | 0.3394 | 0.0696 |
| MCF7 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 874 | 4012 | 0.2179 | -0.1724 |
| MCF7 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 491 | 4012 | 0.1226 | -0.4072 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 631 | 4012 | 0.1570 | -0.3152 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 636 | 4012 | 0.1589 | -0.3108 |
| MCF7 | A443654 | 10 | uM | LJP6 | 72 | hr | 1209 | 403 | 4012 | 0.1003 | -0.4714 |
| MCF7 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3687 | 4203 | 0.8774 | 0.8595 |
| MCF7 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4035 | 4203 | 0.9607 | 0.9562 |
| MCF7 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4099 | 4203 | 0.9746 | 0.9707 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4189 | 4203 | 0.9961 | 0.9949 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 4070 | 4203 | 0.9685 | 0.9647 |
| MCF7 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1209 | 409 | 4203 | 0.0977 | -0.4537 |
| MCF7 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2135 | 4012 | 0.5327 | 0.3894 |
| MCF7 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1604 | 4012 | 0.3994 | 0.1755 |
| MCF7 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1212 | 4012 | 0.3026 | 0.0015 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1216 | 4012 | 0.3034 | 0.0030 |
| MCF7 | Pictilisib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1112 | 4012 | 0.2780 | -0.0470 |
| MCF7 | Pictilisib | 10 | uM | LJP6 | 72 | hr | 1209 | 903 | 4012 | 0.2255 | -0.1558 |
| MCF7 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3272 | 4203 | 0.7800 | 0.7418 |
| MCF7 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3009 | 4203 | 0.7150 | 0.6576 |