LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1826 | 4168 | 0.4382 | 0.1826 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1700 | 4168 | 0.4079 | 0.1297 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1673 | 4168 | 0.4016 | 0.1176 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 72 | hr | 1401 | 1658 | 4168 | 0.3980 | 0.1131 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1663 | 4168 | 0.3987 | 0.1139 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1649 | 4168 | 0.3954 | 0.1083 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1741 | 4168 | 0.4176 | 0.1476 |
| SK-BR-3 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1615 | 4168 | 0.3874 | 0.0940 |
| SK-BR-3 | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1571 | 4168 | 0.3770 | 0.0753 |
| SK-BR-3 | WYE-125132 | 10 | uM | LJP6 | 72 | hr | 1401 | 1467 | 4168 | 0.3524 | 0.0296 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1447 | 4245 | 0.3420 | 0.0205 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1398 | 4245 | 0.3304 | -0.0026 |
| SK-BR-3 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1290 | 4245 | 0.3057 | -0.0495 |
| SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1403 | 4245 | 0.3314 | 0.0006 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1375 | 4245 | 0.3255 | -0.0108 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 72 | hr | 1401 | 1426 | 4245 | 0.3370 | 0.0111 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4553 | 4245 | 1.0737 | 1.0925 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4341 | 4245 | 1.0247 | 1.0323 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4175 | 4245 | 0.9845 | 0.9807 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4131 | 4245 | 0.9758 | 0.9716 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3883 | 4245 | 0.9215 | 0.9020 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 72 | hr | 1401 | 3594 | 4245 | 0.8528 | 0.8126 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4260 | 4245 | 1.0049 | 1.0073 |
| SK-BR-3 | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4234 | 4245 | 1.0001 | 1.0022 |
| SK-BR-3 | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4602 | 4245 | 1.0878 | 1.1104 |