LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1898 | 4012 | 0.4743 | 0.2983 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1439 | 4012 | 0.3589 | 0.1055 |
| MCF7 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1226 | 4012 | 0.3062 | 0.0084 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1079 | 4012 | 0.2695 | -0.0647 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 745 | 4012 | 0.1861 | -0.2443 |
| MCF7 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 1209 | 647 | 4012 | 0.1615 | -0.3045 |
| MCF7 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2945 | 4012 | 0.7336 | 0.6714 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 2415 | 4012 | 0.6031 | 0.4931 |
| MCF7 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1937 | 4012 | 0.4829 | 0.3126 |
| MCF7 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1567 | 4012 | 0.3909 | 0.1611 |
| MCF7 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1407 | 4012 | 0.3510 | 0.0913 |
| MCF7 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 1209 | 972 | 4012 | 0.2425 | -0.1190 |
| MCF7 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2151 | 4012 | 0.5370 | 0.3959 |
| MCF7 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1579 | 4012 | 0.3938 | 0.1664 |
| MCF7 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1317 | 4012 | 0.3284 | 0.0499 |
| MCF7 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1028 | 4012 | 0.2564 | -0.0902 |
| MCF7 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1021 | 4012 | 0.2546 | -0.0938 |
| MCF7 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 1209 | 608 | 4012 | 0.1517 | -0.3285 |
| MCF7 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1482 | 4012 | 0.3686 | 0.1218 |
| MCF7 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1411 | 4012 | 0.3520 | 0.0931 |
| MCF7 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1313 | 4012 | 0.3274 | 0.0482 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1216 | 4012 | 0.3030 | 0.0023 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1158 | 4012 | 0.2889 | -0.0252 |
| MCF7 | Torin1 | 10 | uM | LJP6 | 72 | hr | 1209 | 1000 | 4012 | 0.2490 | -0.1056 |
| MCF7 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 1120 | 4203 | 0.2671 | -0.0417 |