LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 658 1198 3761 0.3185 0.2689
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 658 1208 3761 0.3212 0.2728
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 658 1163 3761 0.3092 0.2538
Hs 578T WYE-125132
3.33
uM
LJP6
 72
hr
 658 1129 3761 0.3002 0.2390
Hs 578T WYE-125132
10
uM
LJP6
 72
hr
 658 1014 3761 0.2698 0.1877
Hs 578T Barasertib
0.04
uM
LJP5
 72
hr
 658 1259 3933 0.3203 0.2862
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 658 1213 3933 0.3086 0.2676
Hs 578T Barasertib
0.37
uM
LJP5
 72
hr
 658 1162 3933 0.2953 0.2460
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 658 1217 3933 0.3095 0.2691
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 658 1155 3933 0.2936 0.2436
Hs 578T Barasertib
10
uM
LJP5
 72
hr
 658 938 3933 0.2386 0.1474
Hs 578T Vemurafenib
0.04
uM
LJP5
 72
hr
 658 4080 3933 1.0374 1.0286
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 658 4031 3933 1.0248 1.0190
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 658 3892 3933 0.9895 0.9917
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 658 3708 3933 0.9429 0.9549
Hs 578T Vemurafenib
3.33
uM
LJP5
 72
hr
 658 3040 3933 0.7729 0.8097
Hs 578T Vemurafenib
10
uM
LJP5
 72
hr
 658 1915 3933 0.4870 0.5130
Hs 578T Enzastaurin
0.04
uM
LJP5
 72
hr
 658 4173 3933 1.0610 1.0463
Hs 578T Enzastaurin
0.12
uM
LJP5
 72
hr
 658 3975 3933 1.0107 1.0082
Hs 578T Enzastaurin
0.37
uM
LJP5
 72
hr
 658 4046 3933 1.0285 1.0218
Hs 578T Enzastaurin
1.11
uM
LJP5
 72
hr
 658 4153 3933 1.0560 1.0426
Hs 578T Enzastaurin
3.33
uM
LJP5
 72
hr
 658 4086 3933 1.0389 1.0297
Hs 578T Enzastaurin
10
uM
LJP5
 72
hr
 658 3433 3933 0.8728 0.8971
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 658 2361 3761 0.6280 0.6621
Hs 578T Palbociclib
0.12
uM
LJP6
 72
hr
 658 2070 3761 0.5502 0.5768