LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 1204 | 3673 | 0.3279 | 0.0548 |
| BT-20 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 1979 | 3673 | 0.5389 | 0.4023 |
| BT-20 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2700 | 3673 | 0.7356 | 0.6766 |
| BT-20 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3487 | 3673 | 0.9494 | 0.9414 |
| SK-BR-3 | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1645 | 4168 | 0.3949 | 0.1075 |
| SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1708 | 4168 | 0.4100 | 0.1342 |
| SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1958 | 4168 | 0.4696 | 0.2362 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2371 | 4168 | 0.5690 | 0.3973 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3262 | 4168 | 0.7821 | 0.7091 |
| MCF7 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2257 | 4012 | 0.5628 | 0.4342 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1575 | 4012 | 0.3927 | 0.1636 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1396 | 4012 | 0.3483 | 0.0859 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1160 | 4012 | 0.2889 | -0.0252 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1057 | 4012 | 0.2635 | -0.0756 |
| MCF7 | ZSTK474 | 10 | uM | LJP6 | 72 | hr | 1209 | 925 | 4012 | 0.2310 | -0.1435 |