LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T CP724714
0.12
uM
LJP5
 72
hr
 658 3609 3933 0.9174 0.9342
Hs 578T CP724714
3.33
uM
LJP5
 72
hr
 658 3490 3933 0.8873 0.9094
Hs 578T CP724714
10
uM
LJP5
 72
hr
 658 3308 3933 0.8409 0.8698
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 658 409 3761 0.1087 -0.1740
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 658 372 3761 0.0988 -0.2037
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 658 4001 3933 1.0171 1.0130
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 658 3900 3933 0.9916 0.9933
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 658 3525 3933 0.8962 0.9168
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 658 3388 3933 0.8615 0.8877
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 658 897 3761 0.2387 0.1311
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 658 423 3761 0.1127 -0.1611
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 658 341 3761 0.0908 -0.2312
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 658 304 3761 0.0811 -0.2642
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 658 398 3761 0.1060 -0.1812
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 658 272 3761 0.0723 -0.2965
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 658 1200 3761 0.3192 0.2698
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 658 1002 3761 0.2665 0.1819
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 658 848 3761 0.2256 0.1060
Hs 578T AZD8055
10
uM
LJP6
 72
hr
 658 103 3761 0.0276 -0.5223
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 658 4138 3761 1.1003 1.0774
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 658 4009 3761 1.0664 1.0517
Hs 578T CP466722
0.12
uM
LJP5
 72
hr
 658 4061 3933 1.0324 1.0246
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 658 3992 3933 1.0150 1.0115
Hs 578T GW843682X
0.12
uM
LJP6
 72
hr
 658 1516 3761 0.4032 0.3925
Hs 578T GW843682X
0.04
uM
LJP6
 72
hr
 658 3186 3761 0.8471 0.8721