LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1209 4445 4203 1.0582 1.0640
MCF7 Sigma A6730
3.33
uM
LJP5
 72
hr
 1209 2001 4203 0.4764 0.3230
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1209 3748 4203 0.8918 0.8764
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1209 3957 4203 0.9412 0.9334
MCF7 HG-5-113-01
0.12
uM
LJP5
 72
hr
 1209 3723 4203 0.8869 0.8705
MCF7 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1209 2153 4203 0.5125 0.3779
MCF7 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1209 1448 4203 0.3457 0.1064
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1209 1316 4203 0.3136 0.0480
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1209 569 4203 0.1358 -0.3430
MCF7 SB590885
0.04
uM
LJP5
 72
hr
 1209 3687 4203 0.8774 0.8595
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1209 4412 4203 1.0522 1.0586
MCF7 SB590885
0.37
uM
LJP5
 72
hr
 1209 4099 4203 0.9746 0.9707
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1209 4175 4203 0.9932 0.9920
MCF7 Seliciclib
1.11
uM
LJP5
 72
hr
 1209 3350 4203 0.7974 0.7628
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1209 4156 4203 0.9898 0.9893
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1209 1390 4203 0.3315 0.0809
MCF7 CP466722
1.11
uM
LJP5
 72
hr
 1209 3824 4203 0.9113 0.8991
MCF7 Dasatinib
0.12
uM
LJP5
 72
hr
 1209 2258 4203 0.5386 0.4170
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1209 3332 4203 0.7963 0.7620
MCF7 Dasatinib
1.11
uM
LJP5
 72
hr
 1209 1495 4203 0.3557 0.1241
MCF7 CP466722
10
uM
LJP5
 72
hr
 1209 1742 4203 0.4146 0.2244
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1209 3690 4203 0.8761 0.8552
MCF7 Neratinib
0.12
uM
LJP5
 72
hr
 1209 3310 4203 0.7868 0.7488
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1209 2969 4203 0.7079 0.6502
MCF7 PD184352
0.12
uM
LJP5
 72
hr
 1209 3009 4203 0.7150 0.6576