LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD-6482
10
uM
LJP5
 72
hr
 1209 1478 4203 0.3503 0.1121
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1209 4014 4203 0.9547 0.9482
MCF7 NU7441
0.12
uM
LJP5
 72
hr
 1209 3929 4203 0.9360 0.9282
MCF7 NU7441
0.37
uM
LJP5
 72
hr
 1209 3777 4203 0.8990 0.8849
MCF7 NU7441
1.11
uM
LJP5
 72
hr
 1209 3487 4203 0.8305 0.8038
MCF7 NU7441
3.33
uM
LJP5
 72
hr
 1209 3054 4203 0.7274 0.6752
MCF7 NU7441
10
uM
LJP5
 72
hr
 1209 1259 4203 0.2999 0.0219
MCF7 Barasertib
10
uM
LJP5
 72
hr
 1209 1468 4203 0.3504 0.1148
MCF7 Seliciclib
1.11
uM
LJP5
 72
hr
 1209 3350 4203 0.7974 0.7628
MCF7 Vemurafenib
0.37
uM
LJP5
 72
hr
 1209 4347 4203 1.0360 1.0407
MCF7 Vemurafenib
3.33
uM
LJP5
 72
hr
 1209 4259 4203 1.0147 1.0170
MCF7 Vemurafenib
10
uM
LJP5
 72
hr
 1209 3596 4203 0.8555 0.8330
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1209 4156 4203 0.9898 0.9893
MCF7 Enzastaurin
1.11
uM
LJP5
 72
hr
 1209 3959 4203 0.9436 0.9368
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1209 3621 4203 0.8617 0.8409
MCF7 Enzastaurin
10
uM
LJP5
 72
hr
 1209 2911 4203 0.6935 0.6314
MCF7 Crizotinib
0.12
uM
LJP5
 72
hr
 1209 3523 4203 0.8394 0.8147
MCF7 Torin2
0.37
uM
LJP5
 72
hr
 1209 997 4203 0.2378 -0.1018
MCF7 Crizotinib
0.37
uM
LJP5
 72
hr
 1209 3073 4203 0.7306 0.6782
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1209 1502 4203 0.3579 0.1279
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1209 1458 4203 0.3476 0.1101
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1209 1454 4203 0.3463 0.1077
MCF7 Barasertib
1.11
uM
LJP5
 72
hr
 1209 1417 4203 0.3379 0.0926
MCF7 Pelitinib
3.33
uM
LJP5
 72
hr
 1209 1741 4203 0.4143 0.2239
MCF7 Pelitinib
1.11
uM
LJP5
 72
hr
 1209 2812 4203 0.6699 0.6000