LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1203 | 4245 | 0.2839 | -0.0927 |
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1214 | 4168 | 0.2910 | -0.0886 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1401 | 796 | 4245 | 0.1885 | -0.2983 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1401 | 692 | 4168 | 0.1659 | -0.3626 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1401 | 91 | 4245 | 0.0217 | -0.8201 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 1401 | 109 | 4168 | 0.0261 | -0.8036 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1401 | 2339 | 4245 | 0.5562 | 0.3839 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2168 | 4168 | 0.5199 | 0.3189 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1780 | 4245 | 0.4212 | 0.1629 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1639 | 4168 | 0.3929 | 0.1034 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1712 | 4245 | 0.4072 | 0.1362 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1489 | 4168 | 0.3576 | 0.0395 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1652 | 4245 | 0.3952 | 0.1080 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1499 | 4168 | 0.3597 | 0.0436 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1603 | 4245 | 0.3837 | 0.0878 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1469 | 4168 | 0.3530 | 0.0305 |
| SK-BR-3 | Radicicol | 10 | uM | LJP5 | 72 | hr | 1401 | 1094 | 4245 | 0.2583 | -0.1446 |
| SK-BR-3 | Radicicol | 10 | uM | LJP6 | 72 | hr | 1401 | 922 | 4168 | 0.2216 | -0.2335 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4170 | 4245 | 0.9823 | 0.9777 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4473 | 4168 | 1.0732 | 1.0919 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4516 | 4245 | 1.0637 | 1.0790 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3721 | 4168 | 0.8930 | 0.8613 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2157 | 4245 | 0.5074 | 0.3054 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1981 | 4168 | 0.4756 | 0.2464 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1525 | 4245 | 0.3606 | 0.0550 |