LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4163 | 4168 | 0.9990 | 0.9987 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3932 | 4245 | 0.9259 | 0.9054 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3773 | 4168 | 0.9057 | 0.8778 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4082 | 4245 | 0.9644 | 0.9574 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3694 | 4168 | 0.8857 | 0.8493 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3426 | 4245 | 0.7981 | 0.7106 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3240 | 4168 | 0.7767 | 0.7020 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2728 | 4245 | 0.6315 | 0.4648 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2620 | 4168 | 0.6279 | 0.4848 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 1401 | 2449 | 4245 | 0.5696 | 0.3852 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 1401 | 2176 | 4168 | 0.5224 | 0.3200 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1826 | 4245 | 0.4307 | 0.1794 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1637 | 4168 | 0.3929 | 0.1038 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1560 | 4245 | 0.3657 | 0.0619 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1486 | 4168 | 0.3570 | 0.0385 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1489 | 4245 | 0.3495 | 0.0325 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1453 | 4168 | 0.3487 | 0.0230 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1358 | 4245 | 0.3195 | -0.0240 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1420 | 4168 | 0.3410 | 0.0081 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1064 | 4245 | 0.2481 | -0.1724 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1189 | 4168 | 0.2857 | -0.0992 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 1401 | 915 | 4245 | 0.2127 | -0.2496 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 1401 | 772 | 4168 | 0.1856 | -0.3196 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4814 | 4245 | 1.1359 | 1.1686 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4446 | 4245 | 1.0463 | 1.0564 |