LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 72 | hr | 1389 | 1957 | 5905 | 0.3309 | 0.1761 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6255 | 5905 | 1.0608 | 1.0573 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5677 | 5905 | 0.9624 | 0.9637 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5519 | 5905 | 0.9336 | 0.9339 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5906 | 5905 | 1.0024 | 1.0013 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 5117 | 5905 | 0.8677 | 0.8684 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 72 | hr | 1389 | 3490 | 5905 | 0.5918 | 0.5554 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 72 | hr | 1389 | 1663 | 5905 | 0.2820 | 0.0904 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5276 | 5905 | 0.8927 | 0.8934 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 6152 | 5905 | 1.0425 | 1.0406 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 5927 | 5905 | 1.0052 | 1.0049 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 72 | hr | 1389 | 5618 | 5905 | 0.9517 | 0.9533 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5956 | 5905 | 1.0082 | 1.0075 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5842 | 5905 | 0.9887 | 0.9886 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 4267 | 5905 | 0.7211 | 0.7069 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 1389 | 6072 | 5905 | 1.0283 | 1.0270 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 4580 | 5905 | 0.7740 | 0.7660 |
| MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1458 | 5905 | 0.2467 | 0.0226 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 4205 | 5905 | 0.7115 | 0.6984 |
| MCF7 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 2234 | 5905 | 0.3783 | 0.2554 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1796 | 5905 | 0.3043 | 0.1311 |
| MCF7 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1687 | 5905 | 0.2858 | 0.0975 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1814 | 5905 | 0.3069 | 0.1354 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3172 | 5905 | 0.5362 | 0.4818 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4980 | 5905 | 0.8423 | 0.8408 |