LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 XMD16-144
0.12
uM
LJP5
 72
hr
 1334 2327 4033 0.5777 0.4173
BT-20 XMD16-144
0.37
uM
LJP5
 72
hr
 1334 1362 4033 0.3385 0.0129
BT-20 XMD16-144
1.11
uM
LJP5
 72
hr
 1334 1159 4033 0.2874 -0.0848
BT-20 XMD16-144
3.33
uM
LJP5
 72
hr
 1334 1214 4033 0.3013 -0.0575
BT-20 XMD16-144
10
uM
LJP5
 72
hr
 1334 818 4033 0.2030 -0.2640
BT-20 Erlotinib
0.04
uM
LJP5
 72
hr
 1334 3679 4033 0.9124 0.8880
BT-20 Erlotinib
0.12
uM
LJP5
 72
hr
 1334 3804 4033 0.9435 0.9287
BT-20 Erlotinib
0.37
uM
LJP5
 72
hr
 1334 3961 4033 0.9819 0.9769
BT-20 Erlotinib
1.11
uM
LJP5
 72
hr
 1334 3554 4033 0.8814 0.8480
BT-20 Erlotinib
3.33
uM
LJP5
 72
hr
 1334 3753 4033 0.9304 0.9114
BT-20 Erlotinib
10
uM
LJP5
 72
hr
 1334 2541 4033 0.6312 0.4971
BT-20 Gefitinib
0.04
uM
LJP6
 72
hr
 1334 4187 3925 1.0668 1.0848
BT-20 Gefitinib
0.12
uM
LJP6
 72
hr
 1334 4099 3925 1.0441 1.0551
BT-20 Gefitinib
0.37
uM
LJP6
 72
hr
 1334 3831 3925 0.9760 0.9685
BT-20 Gefitinib
1.11
uM
LJP6
 72
hr
 1334 3848 3925 0.9802 0.9739
BT-20 Gefitinib
3.33
uM
LJP6
 72
hr
 1334 3702 3925 0.9429 0.9247
BT-20 Gefitinib
10
uM
LJP6
 72
hr
 1334 3574 3925 0.9103 0.8822
BT-20 Nilotinib
0.04
uM
LJP5
 72
hr
 1334 4101 4033 1.0178 1.0212
BT-20 Nilotinib
0.12
uM
LJP5
 72
hr
 1334 4116 4033 1.0214 1.0269
BT-20 Nilotinib
0.37
uM
LJP5
 72
hr
 1334 4227 4033 1.0488 1.0610
BT-20 Nilotinib
1.11
uM
LJP5
 72
hr
 1334 4129 4033 1.0244 1.0304
BT-20 Nilotinib
3.33
uM
LJP5
 72
hr
 1334 4174 4033 1.0358 1.0451
BT-20 Nilotinib
10
uM
LJP5
 72
hr
 1334 1233 4033 0.3063 -0.0480
BT-20 JNK-9L
0.04
uM
LJP6
 72
hr
 1334 3521 3925 0.8968 0.8643
BT-20 JNK-9L
0.12
uM
LJP6
 72
hr
 1334 3619 3925 0.9224 0.8985