LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Nilotinib
1.11
uM
LJP5
 72
hr
 1389 5707 5905 0.9665 0.9676
MCF7 Nilotinib
3.33
uM
LJP5
 72
hr
 1389 5583 5905 0.9463 0.9480
MCF7 Nilotinib
10
uM
LJP5
 72
hr
 1389 1619 5905 0.2751 0.0756
MCF7 JNK-9L
0.04
uM
LJP6
 72
hr
 1389 4161 5445 0.7679 0.7475
MCF7 JNK-9L
0.12
uM
LJP6
 72
hr
 1389 4020 5445 0.7420 0.7182
MCF7 JNK-9L
0.37
uM
LJP6
 72
hr
 1389 2616 5445 0.4804 0.3779
MCF7 JNK-9L
1.11
uM
LJP6
 72
hr
 1389 1329 5445 0.2443 -0.0227
MCF7 JNK-9L
3.33
uM
LJP6
 72
hr
 1389 957 5445 0.1758 -0.1731
MCF7 JNK-9L
10
uM
LJP6
 72
hr
 1389 1219 5445 0.2244 -0.0649
MCF7 PD0325901
0.04
uM
LJP5
 72
hr
 1389 3848 5905 0.6519 0.6293
MCF7 PD0325901
0.04
uM
LJP6
 72
hr
 1389 3622 5445 0.6627 0.6182
MCF7 PD0325901
0.12
uM
LJP5
 72
hr
 1389 3513 5905 0.5953 0.5600
MCF7 PD0325901
0.12
uM
LJP6
 72
hr
 1389 3310 5445 0.6090 0.5547
MCF7 PD0325901
0.37
uM
LJP5
 72
hr
 1389 3616 5905 0.6136 0.5819
MCF7 PD0325901
0.37
uM
LJP6
 72
hr
 1389 3098 5445 0.5678 0.4983
MCF7 PD0325901
1.11
uM
LJP5
 72
hr
 1389 3226 5905 0.5465 0.4973
MCF7 PD0325901
1.11
uM
LJP6
 72
hr
 1389 2953 5445 0.5427 0.4660
MCF7 PD0325901
3.33
uM
LJP5
 72
hr
 1389 2392 5905 0.4047 0.2961
MCF7 PD0325901
3.33
uM
LJP6
 72
hr
 1389 2287 5445 0.4199 0.2867
MCF7 PD0325901
10
uM
LJP5
 72
hr
 1389 1384 5905 0.2343 -0.0022
MCF7 PD0325901
10
uM
LJP6
 72
hr
 1389 1461 5445 0.2677 0.0226
MCF7 Geldanamycin
0.04
uM
LJP5
 72
hr
 1389 3677 5905 0.6223 0.5931
MCF7 Geldanamycin
0.04
uM
LJP6
 72
hr
 1389 3461 5445 0.6377 0.5915
MCF7 Geldanamycin
0.12
uM
LJP5
 72
hr
 1389 1923 5905 0.3253 0.1671
MCF7 Geldanamycin
0.12
uM
LJP6
 72
hr
 1389 1825 5445 0.3367 0.1498