LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Saracatinib
0.04
uM
LJP6
 72
hr
 1694 11431 11217 1.0191 1.0139
MCF 10A Saracatinib
0.12
uM
LJP6
 72
hr
 1694 10704 11217 0.9545 0.9658
MCF 10A Saracatinib
0.37
uM
LJP6
 72
hr
 1694 10020 11217 0.8934 0.9188
MCF 10A Saracatinib
1.11
uM
LJP6
 72
hr
 1694 7988 11217 0.7121 0.7658
MCF 10A Saracatinib
3.33
uM
LJP6
 72
hr
 1694 5938 11217 0.5294 0.5834
MCF 10A Saracatinib
10
uM
LJP6
 72
hr
 1694 2446 11217 0.2181 0.1440
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 1694 11014 11103 0.9921 0.9941
MCF 10A Sigma A6730
0.12
uM
LJP5
 72
hr
 1694 10798 11103 0.9724 0.9794
MCF 10A Sigma A6730
0.37
uM
LJP5
 72
hr
 1694 10813 11103 0.9738 0.9805
MCF 10A Sigma A6730
1.11
uM
LJP5
 72
hr
 1694 10506 11103 0.9461 0.9595
MCF 10A Sigma A6730
3.33
uM
LJP5
 72
hr
 1694 11000 11103 0.9908 0.9931
MCF 10A Sigma A6730
10
uM
LJP5
 72
hr
 1694 6934 11103 0.6246 0.6804
MCF 10A WH-4-025
0.04
uM
LJP5
 72
hr
 1694 11668 11103 1.0509 1.0368
MCF 10A WH-4-025
0.12
uM
LJP5
 72
hr
 1694 10071 11103 0.9071 0.9292
MCF 10A WH-4-025
0.37
uM
LJP5
 72
hr
 1694 9113 11103 0.8208 0.8594
MCF 10A WH-4-025
1.11
uM
LJP5
 72
hr
 1694 5793 11103 0.5217 0.5734
MCF 10A WH-4-025
3.33
uM
LJP5
 72
hr
 1694 4329 11103 0.3900 0.4132
MCF 10A WH-4-025
10
uM
LJP5
 72
hr
 1694 3251 11103 0.2929 0.2717
MCF 10A R406
0.04
uM
LJP6
 72
hr
 1694 11540 11217 1.0289 1.0210
MCF 10A R406
0.12
uM
LJP6
 72
hr
 1694 11292 11217 1.0067 1.0049
MCF 10A R406
0.37
uM
LJP6
 72
hr
 1694 11086 11217 0.9885 0.9914
MCF 10A R406
1.11
uM
LJP6
 72
hr
 1694 10766 11217 0.9599 0.9701
MCF 10A R406
3.33
uM
LJP6
 72
hr
 1694 10161 11217 0.9062 0.9284
MCF 10A R406
10
uM
LJP6
 72
hr
 1694 8673 11217 0.7736 0.8196
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 1694 1015 11217 0.0905 -0.1719