LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 1694 4209 11103 0.3792 0.3986
MCF 10A GDC-0980
1.11
uM
LJP5
 72
hr
 1694 2526 11103 0.2276 0.1579
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 1694 2387 11103 0.2151 0.1338
MCF 10A GDC-0980
10
uM
LJP5
 72
hr
 1694 2118 11103 0.1908 0.0853
MCF 10A Mitoxantrone
0.04
uM
LJP5
 72
hr
 1694 3239 11103 0.2917 0.2696
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 1694 3196 11217 0.2850 0.2620
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 1694 1687 11103 0.1520 -0.0016
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 1694 1599 11217 0.1426 -0.0211
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 1694 1623 11103 0.1462 -0.0156
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 1694 1479 11217 0.1319 -0.0487
MCF 10A Mitoxantrone
1.11
uM
LJP5
 72
hr
 1694 1422 11103 0.1281 -0.0630
MCF 10A Mitoxantrone
1.11
uM
LJP6
 72
hr
 1694 1380 11217 0.1231 -0.0724
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 1694 775 11103 0.0699 -0.2510
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 1694 630 11217 0.0562 -0.3070
MCF 10A Mitoxantrone
10
uM
LJP5
 72
hr
 1694 992 11103 0.0893 -0.1791
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 1694 697 11217 0.0621 -0.2789
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 1694 9940 11103 0.8953 0.9201
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 1694 9703 11217 0.8651 0.8964
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 1694 7622 11103 0.6865 0.7409
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 1694 7232 11217 0.6445 0.7018
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 1694 4503 11103 0.4057 0.4337
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 1694 4177 11217 0.3722 0.3911
MCF 10A Radicicol
1.11
uM
LJP5
 72
hr
 1694 2365 11103 0.2131 0.1302
MCF 10A Radicicol
1.11
uM
LJP6
 72
hr
 1694 2358 11217 0.2102 0.1276
MCF 10A Radicicol
3.33
uM
LJP5
 72
hr
 1694 1519 11103 0.1368 -0.0414