LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T OSI-027
3.33
uM
LJP6
 72
hr
 765 1165 3101 0.3756 0.2314
Hs 578T OSI-027
10
uM
LJP6
 72
hr
 765 882 3101 0.2847 0.0730
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 765 997 3101 0.3216 0.1400
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 765 923 3101 0.2976 0.0973
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 765 3140 3148 0.9974 0.9974
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 765 3161 3148 1.0043 1.0041
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 765 3091 3148 0.9820 0.9818
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 765 3092 3148 0.9823 0.9822
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 765 2279 3101 0.7348 0.7168
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 765 531 3101 0.1712 -0.1659
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3101 0.0968 -0.3718
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 765 266 3101 0.0862 -0.4158
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3101 0.1604 -0.1920
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3101 0.1504 -0.2176
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3101 0.3617 0.2086
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 765 1030 3101 0.3322 0.1585
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 765 829 3101 0.2677 0.0406
Hs 578T AZD8055
10
uM
LJP6
 72
hr
 765 510 3101 0.1650 -0.1859
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 765 3587 3101 1.1563 1.1491
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 765 3768 3101 1.2151 1.2026
Hs 578T CP466722
0.12
uM
LJP5
 72
hr
 765 3222 3148 1.0236 1.0230
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 765 3368 3148 1.0700 1.0672
Hs 578T CP466722
3.33
uM
LJP5
 72
hr
 765 3075 3148 0.9770 0.9770
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 765 945 3148 0.3003 0.1090
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 765 1005 3148 0.3194 0.1434