LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Saracatinib | 10 | uM | LJP6 | 72 | hr | 765 | 1175 | 3101 | 0.3790 | 0.2368 |
MCF 10A | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11015 | 11217 | 0.9821 | 0.9868 |
MCF 10A | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1694 | 9876 | 11217 | 0.8806 | 0.9089 |
MCF 10A | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1694 | 5668 | 11217 | 0.5053 | 0.5570 |
MCF 10A | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1859 | 11217 | 0.1657 | 0.0341 |
MCF 10A | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1694 | 970 | 11217 | 0.0865 | -0.1851 |
MCF 10A | GW843682X | 10 | uM | LJP6 | 72 | hr | 1694 | 715 | 11217 | 0.0638 | -0.2712 |
MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11315 | 11217 | 1.0086 | 1.0060 |
MCF 10A | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 10974 | 11217 | 0.9783 | 0.9839 |
MCF 10A | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 10967 | 11217 | 0.9776 | 0.9833 |
MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10827 | 11217 | 0.9651 | 0.9740 |
MCF 10A | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 9454 | 11217 | 0.8429 | 0.8785 |
MCF 10A | Nintedanib | 10 | uM | LJP6 | 72 | hr | 1694 | 10976 | 11217 | 0.9784 | 0.9840 |
Hs 578T | R406 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3111 | 3101 | 1.0034 | 1.0033 |
Hs 578T | R406 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2759 | 3101 | 0.8899 | 0.8877 |
Hs 578T | R406 | 0.37 | uM | LJP6 | 72 | hr | 765 | 2546 | 3101 | 0.8212 | 0.8141 |
Hs 578T | R406 | 1.11 | uM | LJP6 | 72 | hr | 765 | 2365 | 3101 | 0.7626 | 0.7488 |
Hs 578T | R406 | 3.33 | uM | LJP6 | 72 | hr | 765 | 1840 | 3101 | 0.5932 | 0.5440 |
Hs 578T | R406 | 10 | uM | LJP6 | 72 | hr | 765 | 646 | 3101 | 0.2084 | -0.0805 |
Hs 578T | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 765 | 440 | 3101 | 0.1420 | -0.2401 |
Hs 578T | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 765 | 400 | 3101 | 0.1291 | -0.2757 |
Hs 578T | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 765 | 468 | 3101 | 0.1509 | -0.2162 |
Hs 578T | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 765 | 504 | 3101 | 0.1627 | -0.1868 |
Hs 578T | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 765 | 527 | 3101 | 0.1702 | -0.1684 |
Hs 578T | BI-2536 | 10 | uM | LJP6 | 72 | hr | 765 | 401 | 3101 | 0.1294 | -0.2740 |