LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Sorafenib
0.37
uM
LJP6
 72
hr
 1389 4946 5445 0.9088 0.9046
MCF7 Sorafenib
1.11
uM
LJP6
 72
hr
 1389 4660 5445 0.8537 0.8430
MCF7 Sorafenib
3.33
uM
LJP6
 72
hr
 1389 4391 5445 0.8027 0.7828
MCF7 Sorafenib
10
uM
LJP6
 72
hr
 1389 1891 5445 0.3485 0.1704
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1389 1519 5445 0.2789 0.0452
MCF7 AZD7762
1.11
uM
LJP6
 72
hr
 1389 1327 5445 0.2444 -0.0227
MCF7 AT-7519
0.12
uM
LJP6
 72
hr
 1389 2530 5445 0.4655 0.3558
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1389 1098 5445 0.2015 -0.1148
MCF7 GW843682X
1.11
uM
LJP6
 72
hr
 1389 1547 5445 0.2835 0.0527
MCF7 AZD7762
10
uM
LJP6
 72
hr
 1389 771 5445 0.1412 -0.2608
MCF7 AT-7519
0.37
uM
LJP6
 72
hr
 1389 755 5445 0.1389 -0.2665
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1389 1577 5445 0.2898 0.0624
MCF7 HG-5-88-01
0.12
uM
LJP6
 72
hr
 1389 3585 5445 0.6584 0.6171
MCF7 AZD8055
0.12
uM
LJP6
 72
hr
 1389 1399 5445 0.2563 -0.0001
MCF7 AT-7519
1.11
uM
LJP6
 72
hr
 1389 553 5445 0.1017 -0.3754
MCF7 AZD8055
0.37
uM
LJP6
 72
hr
 1389 1451 5445 0.2657 0.0181
MCF7 Alvocidib
0.04
uM
LJP6
 72
hr
 1389 1631 5445 0.2990 0.0802
MCF7 Alvocidib
0.12
uM
LJP6
 72
hr
 1389 565 5445 0.1037 -0.3695
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1389 489 5445 0.0896 -0.4128
MCF7 Alvocidib
1.11
uM
LJP6
 72
hr
 1389 486 5445 0.0890 -0.4155
MCF7 Alvocidib
3.33
uM
LJP6
 72
hr
 1389 468 5445 0.0859 -0.4251
MCF7 Alvocidib
10
uM
LJP6
 72
hr
 1389 509 5445 0.0933 -0.4010
MCF7 GW843682X
0.04
uM
LJP6
 72
hr
 1389 4561 5445 0.8379 0.8267
MCF7 GW843682X
0.12
uM
LJP6
 72
hr
 1389 3078 5445 0.5636 0.4888
MCF7 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1389 3595 5445 0.6587 0.6149