LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WH-4-025
1.11
uM
LJP5
 72
hr
 765 450 3148 0.1431 -0.2298
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 765 399 3148 0.1268 -0.2751
Hs 578T WH-4-025
10
uM
LJP5
 72
hr
 765 226 3148 0.0718 -0.4499
Hs 578T R406
0.04
uM
LJP6
 72
hr
 765 3111 3101 1.0034 1.0033
Hs 578T R406
0.12
uM
LJP6
 72
hr
 765 2759 3101 0.8899 0.8877
Hs 578T R406
0.37
uM
LJP6
 72
hr
 765 2546 3101 0.8212 0.8141
Hs 578T R406
1.11
uM
LJP6
 72
hr
 765 2365 3101 0.7626 0.7488
Hs 578T R406
3.33
uM
LJP6
 72
hr
 765 1840 3101 0.5932 0.5440
Hs 578T R406
10
uM
LJP6
 72
hr
 765 646 3101 0.2084 -0.0805
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 765 440 3101 0.1420 -0.2401
Hs 578T BI-2536
0.12
uM
LJP6
 72
hr
 765 400 3101 0.1291 -0.2757
Hs 578T BI-2536
0.37
uM
LJP6
 72
hr
 765 468 3101 0.1509 -0.2162
Hs 578T BI-2536
1.11
uM
LJP6
 72
hr
 765 504 3101 0.1627 -0.1868
Hs 578T BI-2536
3.33
uM
LJP6
 72
hr
 765 527 3101 0.1702 -0.1684
Hs 578T BI-2536
10
uM
LJP6
 72
hr
 765 401 3101 0.1294 -0.2740
Hs 578T A443654
0.04
uM
LJP6
 72
hr
 765 1997 3101 0.6437 0.6075
Hs 578T A443654
0.12
uM
LJP6
 72
hr
 765 1319 3101 0.4251 0.3080
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 765 694 3101 0.2236 -0.0486
Hs 578T A443654
1.11
uM
LJP6
 72
hr
 765 397 3101 0.1281 -0.2776
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 765 321 3101 0.1036 -0.3494
Hs 578T A443654
10
uM
LJP6
 72
hr
 765 269 3101 0.0869 -0.4047
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 765 3790 3148 1.2041 1.1904
Hs 578T SB590885
0.12
uM
LJP5
 72
hr
 765 3734 3148 1.1863 1.1744
Hs 578T SB590885
0.37
uM
LJP5
 72
hr
 765 3748 3148 1.1907 1.1785
Hs 578T SB590885
1.11
uM
LJP5
 72
hr
 765 3789 3148 1.2038 1.1903